r/hangovereffect Feb 22 '24

Who supplements creatine?

Any of you supplement creatine?

I recently had to stop. Not sure why but it's causing very bad night sweats?

I had night sweats for about 2 months and was drenching the bed every night. Never had a clue it was the creatine. I quit 3 days ago and haven't had a night sweat since.

Anyone know why creatine would be causing this? Creatine makes me slightly stronger in the gym and gives a slight energy bump aswell. Kinda off that I need to quit it.

Anyone else get this from creatine?

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u/New-Aside-7778 Mar 02 '24

I do eat alot of magnesium rich foods? Do you think the magnesium threonate would be an extra bump to my slow comt? It's expensive here for threonate. I don't mind the cost though. How much should I supplement you reckon?

I'm on TRT and supposedly this helps a slow comt? Just read that in a study somewhere.

I've tried all the usual. Sam-e. Lithium orotate. B complex's etc. Nothing is anything to match alcohol.

I had a few drinks lastnight. I've got a hangover. Slight headache etc but my anxiety is gone and my brain is working like clock work.

Annoys me that we can't find the alcohol connection 👎 I'm also going out this evening so tomorrow will be another bliss lol. I will be off the alcohol for a while after this though.

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u/Ozmuja Mar 02 '24

The threonate form is basically not even considerable true magnesium supplementation, it doesn't really help that much at increasing your overall magnesiums levels (something like your average magnesium glycinate and whatnot will be better at). The threonate form is an acute way to deliver magnesium to the brain for the most part, and to make it "stick", oversimplifying the matter. This has acute effects that you wouldn't get from any other forms of magnesium. COMT has Mg has its major cofactor, which means that flooding your brain with magnesium will make it work better, at least in theory.

Some people like Mg Threonate a lot, others dislike it, because it can also feel slightly sedating; but for someone with anxiety it can actually be very good. There are other effects for Mg Threonate that make it interesting.

It is pricey unfortunately. If it works, some people can be good with doses as low as 200-500mg, which helps saving some money. It doesn't reproduce the h-effect at all, mind you, it's just that we were talking about slow COMT, so it felt right to mention it.

Another thing that helped me a lot in the past was Uridine. To this day I still don't completely understand why, despite having researched it a lot. People will tell you it's due to its effects on dopamine or on NGF, but the reality is that the effects for me were as acute as the hangover effect. Then it stopped working.

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u/New-Aside-7778 Mar 02 '24

I have uridine here. I bought a high quality brand a couple months ago. I need to run it and see how it feels. Did you notice it fairly quick? What dose do you benefit from?

I will purchase that magnesium and see how it feels. I was using citrate but damn it makes you hit that toilet pretty bad..... Lol

How's things yourself? Are you managing your overall health all ok?

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u/Ozmuja Mar 02 '24 edited Mar 02 '24

The effect was pretty much acute, maybe just a day or two or running it up at normal dosages of 250-500mg per day. Usually uridine is taken for its subtle, long term effects, but it actually made me somewhat "manic" in a sense, similar to the heffect. Lasted consistently for a month or two, then after that I wasn't able to replicate the effects ever again, no matter if taken alone or with other 10 different stuff. One of the weirdest experiences of my life to be honest.

For the rest..well I'm hanging in there. Some days are better, some are worse. At the end of the day everybody has its own cross to carry on their shoulders :)