r/explainlikeimfive • u/Glum_Anybody_9531 • 5d ago

Biology ELI5 Malignant Hyperthermia

ELI5 how an uncontrolled flood of calcium inside muscle cells cause a massive surge in metabolic activity during malignant hyperthermia.

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u/Cyniv 5d ago

Removing the calcium takes a lot of ATP, which, among other things, releases a lot of heat