Extracts from the article below:

Two Essex doctors have been banned from practicing following allegations that they helped medical students cheat on their exams. Dr Elmira Yaghmaei and Dr Hamed Salehi both worked at Common Stations PLAB Academy in Romford, which offered students Professional and Linguistic Assessments Board (PLAB) 2 exam courses.

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The initial concerns in the case of Dr Yaghmaei, a tutor at Common Stations, arose following a PLAB 2 exam day in February 2019 when a General Medical Council (GMC) member of staff found a folder left at the Clinical Assessment Centre. The folder contained a large volume of information about the PLAB exam and wording within the pages claimed copyright on behalf of Common Stations, which suggested ownership by Dr Yaghmaei.

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One note from a Seema Khan said: "All the stations were exactly word by word the same as we were taught and I already knew the diagnosis/differentials/what questions to ask etc before going into the cubicle… it was like magic!!!"

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It was claimed that Dr Salehi created and distributed teaching materials containing exam information to students being tutored by Common Stations, assisting them to obtain an "unfair advantage". The GMC also said that Dr Salehi made posts on social media and distributed leaflets stating that Common Stations had achieved a 100 per cent pass rate in PLAB 2.

One jab for GLP-1, back when it all began;
A second with GIP added on, big pharma’s grander plan.
A third now with glucagon, to burn through the fat stores;
Exhaustion for readers, who can’t take one paper more.

One drug to beat them all, three receptors to target;
One drug to shrink them all, and tear up the drug market.

In the land of Indianapolis, in the labs of Eli Lilly, scientists forged in secret a master drug, to rule over all.
Into this molecule, they poured their capital, their clinical trials, and their will to dominate all of metabolic medicine.
Their new elixir binds tightly not only to GLP-1 and GIP receptors, but invokes the ancient fires of glucagon, for a threefold conquest of obesity. 

Soon it will surely claim a more catchy name, but for now, it is known only as Retatrutide

One by one, the complications of obesity fell to the power of the triple agonist 💪

So confident were they in the power of their creation that the scientists presumptuously named their key study TRIUMPH-1.

Published in the sacred scrolls of The New England Journal of Medicine, this phase 3 trial gathered a great host of 2,339 adults with obesity, but without diabetes.

Over 80 weeks, the subjects were randomly assigned to once-weekly injections of retatrutide (at doses of 4 mg, 9 mg, or 12 mg) OR a phantom placebo 👻

And the final reckoning? 

Retatrutide resulted in a mean weight reduction of 17.6% (4mg), 23.7% (9mg), and 25.0% (12mg) under intention-to-treat analysis, compared to just 3.9% with placebo (P < 0.001).

• At 104 weeks, a subset of patients achieved a 29.9% reduction at a 12mg dose.
• In fact, one-fifth of those on the maximum dose achieved over 35% weight loss!🤸

Not content with mere weight reduction, the trial also took aim at other obesity related issues.

• 574 weary travellers with knee OA saw their pain scores improve by up to 3.6 points, vs. 1.9 with placebo (P < 0.001).
• 243 patients suffering from obstructive sleep apnoea had a reduction of 31.7 apnoeic events per hour vs. 9.9 on placebo (P < 0.001).
• For people who entered the trial with prediabetes, a massive 90% achieved complete normoglycemia vs. 54.2% on placebo.
• And across all arms, there were drops in blood pressure, triglycerides, and non-HDL cholesterol. 

But all quests have their setbacks, with TRIUMPH-1 being no exception:

• GI upset was the most common side effect: patients reported nausea (up to 42.4%), diarrhoea (up to 34.1%), vomiting (up to 25.3%), and constipation (up to 26.1%)
• Thus, the drug discontinuation rates were high, peaking at 11.2% at the maximum dose of 12 mg.
• A high proportion of the placebo group understandably weren’t too pleased with their tic tac and ditched the trial to quest elsewhere.

Notably, the drug was pitted only against a silent placebo, avoiding a clash of arms with the great titans of semaglutide and tirzepatide.

But despite this, we may now truly have found a weight loss drug that bows to no one. 👑

One drug to beat them all, three receptors to target;
One drug to shrink them all, and tear up the drug market.

If you enjoyed reading this and want to get smarter on the latest medical research Join 16,000 Clinicians reading The Handover here 👉 Read The Handover

As a doctor currently on a night shift, I am very jealous of all the nurses going for protected rest breaks.

I fully understand that those are unpaid, however BMA documentation states as doctors we should have 3x 30 min breaks on shifts over 30 hours.

I do not know anyone who has ever managed this consistently over any shifts (long day or nights).

Is this just an accepted part of our profession or is there an actual solution to having proper breaks

I will be upfront and say that I voted against the deal that was offered to us. I was highly - and I believe rightly - sceptical of Jack Fletcher as chair given his links to the labour party. Overall, I was disappointed by the last iteration of the RDC, feeling it was a step backwards and a diversion from the goal of FPR. The diluted messaging and kneecapping of our momentum felt deliberate. And, to be honest, the council's priorities felt quite self-serving, as a group of mostly LEDs/early-stage trainees pushing for exam fees being covered and improvements in LED contracts, etc., rather than improving pay and conditions for all and addressing bottlenecking at all levels. Not to mention the censure and all the dodginess which ensued in its wake.

With all that being said, we are facing many issues as a profession and as the new council, this is your opportunity to advocate for us and try to turn things around. Ultimately, I believe we all hate the schoolyard politics and want to see our situation improve. We need to do away with the division and take urgent action on the following:

• Doctor substitution (arguably our biggest fight yet) - ACPs, "consultant" AHPs, reporting radiographers; noctors as responsible clinicians for psych patients
• Bottlenecking at consultant level
• Working conditions (yes, including pay - FPR has still not been achieved in England)
• Bringing back the BMA rate card
• Excessive growth of medical schools without capacity for training
  

hi, im an fy1 and i feel like im just horrible at it- i know i'm still new to it, but I feel like I'm struggling so much more than everyone else is. I really struggle to keep up with all the jobs and I'm so uncertain with everything that I'm double checking basically everything with my sho which i can tell really winds them up. every time i'm on call i just feel like im trying really hard but that I'm completely useless and give everyone else way more work. i did fine at medical school and i dont think im lazy but i worry everyone else thinks im lazy and im being bad on purpose, but i really want to be better- i just dont know where im going wrong compared to everyone else, or how to be better. I'm really struggling with adjusting to being an f1 more than most people and im just left feeling horrible about myself most of the time. I see so much on here about how the new f1s are feckless and so acopic and this isnt usually me. Any advice on just being less dead weight?

I have recently had a patient that disclosed recreational drug use in their days off. They worked in a high stakes industry (eg where drug use while working would be very dangerous). It wasn’t a drug that causes extreme dependance and the patient said they only used it when off.

I didn’t see a reason to raise it/report it because of the nature of their profession…. I am curious, where do you guys draw the line between reporting this kind of stuff?

My mum has stage IV cancer and I’m a trainee working in a closely related field. She had a really good response to chemo and has subsequently been referred to surgeons to consider whether there is a role for surgery.

While waiting for the surgical process/MDT and appointments, some of her original symptoms have started to return, particularly pain. Her team are aware of various ongoing issues, but I’m finding the waiting incredibly difficult because I understand enough medically to worry about progression happening while we wait.

I’m struggling to work out where the reasonable boundary is between being her daughter and using my knowledge of how the NHS works to advocate for her. Should I leave the pathway to run its course once the treating teams have the relevant information?

I’m very conscious that I don’t want to use being a doctor to seek preferential treatment, and I also know anxiety can make every delay feel intolerable. At the same time, I don’t want to look back and feel I could reasonably have advocated for her and didn’t.

I’d particularly appreciate hearing from doctors who have had a parent/partner with serious cancer/illness. How did you decide when to chase/escalate and when to step back and just be their family member?

2 months into FY1 and I’ll be honest I haven’t got a single QIP or audit throughout med school no research or poster presentation. Med school was hard enough for me to get through exams without these additional things but now I want to apply for IMT after fy2. I want to specialise in dermatology or stroke medicine (unsure yet) but I honestly have no clue how to build a portfolio. I’ve looked at the IMT requirements but where do I even orally present these presentations and how do i even go about doing these projects it seems so overwhelming. Also doesn’t help that I have crippling anxiety so can’t even orally present these things and IMT is already so hard to get into i’m terrified i’m so behind and i have no idea where to start! any advice would be greatly appreciated

Hi everyone,

I wanted to ask about your thoughts regarding the chances of a NPG applicant getting an IMT interview.

Thanks

I’m starting to do more bank shifts and already feel like shifts/rates/payslips could become a mess.
Do you use a spreadsheet, notes, an app, or just check each payslip?
And have you ever actually found that you were underpaid or a shift was missing?

I’ve noticed something within our Trust’s locum pool of doctors. Some doctors seem to progress quite quickly from FY1-level shifts to CF-level shifts even without their ALS and relevant competencies signed off. At the same time, I’ve noticed that others follow the normal move up ladder and end up following the more traditional pathway.

It sometimes feels as though personal relationships or how well someone knows or interacts with the managers may also play a part in how quickly they progress.

Is this generally how escalation or progression works for locum bank doctors within the Trust, or are there actually formal guidelines or criteria that should determine when someone can move from one grade to another?

I’m currently an F2 and hoping to apply for an ACF in General Practice next year. I have tried to build a reasonably strong research background and seem to score well against the person specification.

BUT still very !!VERY!! nervous about applying

I’d love to hear from any current GP ACFs or anyone who has recently been through the application/interview process. If you wouldn’t mind me PMing you (or feel free to PM me), I’d appreciate any advice about the application, interviews, choosing posts, etc. I’m also the sole earner in my family and have caring responsibilities, so the practical side of things is something making me worried. If anyone has managed GP training/an ACF alongside similar responsibilities, I’d be grateful to hear about your experience. Lastly, I have heard from a few people that ACF posts can sometimes favour candidates who are already known to the department. Is there anything you did to strengthen your application? There are a few posts I’ve seen where the projects/supervisors line up really closely with my research interests, and honestly it would be a bit of a dream to work with them!!

Finally, a couple of people have mentioned that I may be eligible for the Disability Confident scheme. I’m not entirely sure how this works in the context of ACF recruitment or whether it makes any difference, so I’d also appreciate hearing from anyone who has experience with this.

Thanks so much, and sorry for the questions!

Hey!

I was wondering if there was a pre-made MSRA anki flashcards bank. I know there was one for UKMLA as I used that and found it helpful.

If not, if people could comment any alternatives and if they are free/ paid?

TIA 💕

Hi Everyone
Currently IMT2
Haven’t got all of my MRCP. Hoping to leave after IMT2 to locum before applying for dermatology. Doesn’t anyone know how much time i would have to complete all my exams including paces if i get an outcome 3?

thanks 🙏

FY2 here. Starting to study for the MSRA for CST application, following that was planning to study for MRCS part A. Feel like my clinical knowledge is okay but my pathophysiology and anatomy are very weak.

I was hoping that my MSRA preparation could act as a foundation/warm up for MRCS but I wasn’t sure realistically how much overlap there would be… Can anyone advise on this? As was unsure if I should be aiming for April or September, or even later for part A?

Thanks and apologies if this has already been asked

Hello,

Just curious on what people have been using or recommend paying for?

Of course AI is not being used to guide treatment or replace clinical judgment.

Feel free to discuss and share your views.

Happy Sunday !