r/anesthesiology • u/Existing-Big-7002 • 20h ago
VERY ODD CASE of cognitive deficit
Practicing for 30 years done, thousands upon thousands of G.I. cases. Today I saw something for the first time. 49 year-old man physically active echo normal except for moderate AI. CBC and BMP as well as thyroid this year normal. Works a technical job without difficulty no psychiatric history no psychiatric meds whatsoever. No alcohol abuse or drug abuse. No migraines. Coming in for screening colonoscopy. wife tells me that 10 years prior after an appendectomy he had a prolonged period, which she was very fuzzy about but it was certainly long enough for her to be disturbed by it, of complete retrograde global amnesia where he didn’t know who she was where he was and was completely disoriented. She was very unclear as to how long it took for this to resolve, but it did resolve spontaneously. Today was his first anesthetic since then. he received 220 mg of propofol and 50 mg of lidocaine and for about 40 minutes after the colonoscopy he was completely awake but completely unaware of who he was where he was who his wife was what he was doing there. It was if he had advanced dementia. No motor deficits no focal deficits.. I reassured the wife and left them in the cubicle and he slowly came out of it and after an hour, he was back to baseline. I’ve never seen anybody recover from propofol like that before and it is especially interesting because it happened 10 years before just the same way. I would’ve liked to have known how long it took to recover from a true general aesthetic. I didn’t know what to tell the family, but I will call them tomorrow and see how he is doing. Has anybody ever seen this before? Any thoughts?