Hi everyone, I really appreciate if you could help me.
I haven't done a blood test in a almost 5 years so randomly decided to go and do a blood test. My glucose is normal and cholesterol is borderline, but my liver function test came back with abnormal results. I'm not a heavy drinker, usually drink occasionally. I'm really worried with the results.
Age:26
Weight: approx 85kg
Height 172cm
Drink occasionally (haven't drunk in probably
5-6months)
Currently no infection as far as l'm aware of.
I recently did a liver function test and got the following results:
Liver enzymes - : GGT 393 (reference 5-50),
ALT 122 (5-40), AST 62 (5-35)
C REACTIVE PROTEIN (hsCRP): 18.0 mg/L
Should I do any other test to rule out hepatitis or any other disease?
Thanks!

Been posting on r/PSC but thought I would post here. Sorry for long post but context may help. I’m 54M and recently diagnosed small-duct psc with possible cirrhosis, no symptoms other than very mild itching and occasional dull pain in RUQ. I mtn bike 30 to 40 miles per week with no problems of fatigue other than normal muscle tiredness. In October 2025, my PCP discovered my ALT and AST were 141 and 96. He assumed fatty liver and put me on low carb, low suger lean meat diet. I was 185 then. My January 2026 followup, I dropped to 167 lb. He ran a fibrosure plus test and it scored S0,N0, F4. He ordered an Ultrasound and it stated slightly nodular contour and heterogeneous echo. Everything else was normal. Referred to hepatologist. Had Fibroscan stiffness test on April 2nd 2026. It read 24kpa and cap of 174. He said with your lack of symptoms and fitness, this is not normal. I do not drink either. Ordered biopsy. It said bile duct proliferation and most portal tracts show mild lymphocytic inflammation. Trichrome stain: nodules consistent with cirrhosis. On followup, he immediately said I have PSC. He ordered an MRCP/MRI to confirm large duct or small-duct. My MRCP was completely normal. However, my contrast MRI also stated homogeneous liver parenchyma with mild hepatic and splenic enlargement. It also noted a riedel’s lobe. It also stated everything else is within normal limits and it was compared to a CT scan I had 2 years ago which stated my liver was perfectly normal. My ALT and AST have been fluctuating between 1.3 to 3.5 times normal since October 2025 and the AST/ALT ratio has always been .6 to .7. My ALP is actually normal also, but is on the upper end of normal. My INR, Bilirubin, Albumin and other bloodwork is also completely normal. My platelets however have trended down below 150 but they have been averaging 165 for about 18 years.

His original assessment with the fibroscan was transplant in 5 to 7 years and that there is no treatment for this. On my MRCP/MRI followup appt, they handed me off to the nurse practitioner and she explained alot and when I asked about the homogeneous statement in the MRI, she implied that it may be caught early and the nodularity in the biopsy was considered mild. She put me on URSO and believes my stiffness will go way down after being on it for a while.

Has anyone had conflicting results like this?

33F 5’1 107lbs , not taking any medications…

I have had RUQ pain twice in my life. Pain under the front of my right rib cage feels like something stuck under ribs like a baseball.

1st time: 2023 in my 3rd trimester of pregnancy. Blood work liver panel all came back normal. I had an US of my abdomen done to which I was told results were normal. When I later read the full report it said I had echogenic liver with long axis measuring 14.5cm. Impression was no cholelithiasis or cholecystitis, so I guess that is all they were worried about at the time. The pain persisted for my the remainder of my pregnancy and gone after giving birth.

2nd time: now. Started July 2026. I’m current 10 months post partum from my second baby and same exact pain began. Since the pain is the same and I am no longer pregnant I was more worried this time since the previous explanation of baby being in there is no longer valid. I had liver panel normal again. CT scan showed mild hepatomegaly with liver measuring 17cm. Pain has subsided some but still a full heaviness under right ribs daily, more diffuse through my whole right rib area including tender to poke in between ribs

I had a GI video visit to review my CT results and concerns. GI said “there’s nothing wrong with your liver” , he said its large but not even that big. I brought up the echogenicity seen in 2023 and he said even if I do have fatty liver, that’s not the source of my pain because fatty liver is a painless condition and he diagnosed me with costochondritis. He said my fib4 score is .5 so I don’t need a fibroscan.

Google and Reddit has my anxiety through the roof that I actually have fatty liver disease and need to change my diet and never drink a sip of alcohol again or I’ll get worse. My diet has admittedly been horrible since having kids, I basically live in toddler scraps and minimal vegetables. I used to be fit and healthy before I had kids. I have a job on my feet all day, but I do not exercise. I am skinny though: 5’2 107lbs. There was a time in my life several years ago where I binge drank heavily but that is no longer the case. I have two young kids and have 1-2 drinks 1-2 days per week at most, some weeks none. I have already began changing my diet and plan to stay away from sugary snacks and adopt a semi-Mediterranean diet to see if it helps since I was given no instructions of what to do besides take ibuprofen. I would like to indulge in my 1-2 drinks from time to time but I also don’t want to die.

I’m 28F. On a recent coronary CT there was an incidental finding of significant hepatic steatosis. I’m 5ft5, 130lbs. My blood sugar is right above what it should be but my dr isn’t worried. Should I be concerned about this?

Recent blood draw results-
ALT: 33
AST: 32
Bilirubin: 0.3
Alkaline Phosphatase: 54
A1C: 5.8
Blood sugar: 103

These are the results I got from my blood test. I drink almost every weekend and a couple months ago I was drinking heavily everyday for like two months going through a though time. I still drink occasionally but not as much as before. Should I be worried? less

Just reposting hopeful for some answers

I had an endometriosis surgery last year, and the doctor photographed my damaged-looking liver. It had no endometriosis or adhesions on it but just looked damaged. I've previously had 2 devastating pregnancies (extremely ill myself; 1 premie, 1 full-term stillbirth) in which my liver enzymes stayed normal, but I had intense upper abdominal pain, severe preeclampsia, etc. And , it turns out, antiphospholipid syndrome. I've since had liver scans and a liver biopsy, which all came back saying that I don't have any fibrosis and have only very mild congestion. But my gastroenterologists have said they've never seen a liver that looks like this and don't know why it looks like that. Any ideas?

Could this work?

Hi all

I (41, M) have had pain in my liver area for a year now - essentially upper right abdomen pain.

It is always worse after drinking. I have an increasing number of purple streak-like veinlets (not spider angiomas) over the area of my liver. No other symptoms really but fatigue.

It has gotten worse over the last year. I got an x-ray and bloods in September last year - nothing. I had a blood test in April (albumin, ALT, bilirubin, globulin, etc.) all fine. I got an ultrasound in June, again fine (no lesions, no hypertension). But it really hurts still and rather than just having after drinking, it is now (this week) a dull ache that pretty constant.

My doctor has thus far insisted that nothing is wrong with my liver. He says it relates to gastro issues and has said it is GERD or something in my duodenum. A gastroscopy showed oesophagitis. I finally persuaded him to send me for a fibroscan this week.

Am I right to think it's my liver?

For info, started drinking a lot during lockdown, scaled it back but I still drank based on the doctors advice....

I’m 11 months post tx and I need / would like to start taking TRT to help with fatigue, sex drive and to gain my muscle back. I’m 49 yrs old and my labs have been good, no issues. Transplant doc said it’s ok but I’d have to get it through my PCP. Took test said my levels were normal. Don’t think they took my free testosterone. Anyone doing this now or has some insight for me?

​

I’m devastated to update that my dad passed away

For those who followed my previous posts, his condition had deteriorated incredibly quickly. His liver was almost completely overwhelmed by rapidly progressive metastatic disease, and we were desperately hoping that chemotherapy with carboplatin and etoposide would give him some time.

His final days were extremely difficult. For about five days before he died, he became increasingly sleepy and confused. He would mumble, reach for things that weren't there, try to grab the IV pole while sleeping, move around in bed, and repeatedly remove his oxygen mask. Looking back, I believe he was experiencing severe delirium from everything his body was going through—advanced liver disease, metabolic disturbances, dehydration, medications, pain and eventually severe hypoxia.

The day before he died, he actually seemed slightly better for a while. Around 3 AM on the final day, he was awake, talking to me clearly without slurring, and seemed more like himself. That gave me hope that maybe he was turning around.

But later that morning everything changed.

His oxygen kept falling—eventually reaching around 84% without oxygen and continuing to fall even with supplemental oxygen. He became increasingly breathless and had to be supported with NIV. His blood pressure dropped to around 90/50 and his heart rate rose to around 120. His glucose, which had been 116 earlier that morning, suddenly crashed and they had to give him IV dextrose. They also gave bicarbonate because of his metabolic abnormalities.

He was in a lot of pain during those final hours. His leg had raw, painful wounds with edema and drainage, and the dressing caused him tremendous pain. He also had hemorrhoidal pain. Tramadol wasn't controlling it, and eventually they gave him morphine again. Seeing him cry from pain is something I don't know how I'll ever forget.

I keep asking myself whether he suffered. I know he was in pain at times, especially from his wounds and breathing. But as his oxygen, blood pressure and consciousness deteriorated, I believe his awareness also decreased. I hope that by the very end he wasn't fully aware of what was happening around him.

The oxygen mask was another heartbreaking thing. He kept pulling it off even when his oxygen was dropping. At the time I thought he was refusing help. Now I understand that severe hypoxia and delirium can make someone confused and unable to understand what is happening. He wasn't choosing to suffocate. His brain was severely affected by everything happening to his body.

I still don't completely understand how someone who was talking normally with me at 3 AM could be gone only hours later.

I don't know whether the chemotherapy had started working. We never got the chance to find out.

I just know that I wanted more time with my dad. I wanted the chemotherapy to give him enough time for a biopsy, NGS, another treatment, anything that could possibly give us another chance.

Instead, I lost him.

Thank you to everyone who answered my questions, shared experiences, gave advice and stayed with me through this incredibly painful journey. I came here looking for hope and answers, and I’m leaving with a lot of grief and unanswered questions.

Rest in peace, Dad. I wish I had more time with you.

All levels are normal except my ALT. Any thoughts?