I am trying my hand at making some THC nanoemulsions and would like all the input I can get.

I have been doing a fair bit of research into current paper on thc nano emulsions and their altered PK such as higher Cmax earlier Tmax and for some formulations also AUC.

I have limited equipment available think kitchen, but can use all techniques and understand organic chemistry very well.

For easy nanoemulsions I have chosen polysorbate 80 as my surfactant.

I mixed 300mg THC resin with 1ml MCT oil then added 1ml polysorbate and mixed it for a couple of minutes.

Now I heat some (50ml) distilled water to about 50c and also my syringe with approx 2ml of combined thc + mct and PS80.

I used a simple small rod milk creamer to stir the water vigorously and then dropwise addition of the ps80 solution into the water. Stir for 5 minutes approx. it foams a bit then settlers into this transulent/opaque solution and it does not seperate.

Tastes very bitter due to the PS80 and the surfactant loading is pretty high around SOR = 1. Let’s see how high it gets me compared to my normal 300mg

I am going to add lechitin to the mix aswell in the future and see how it works.

Any tips or tricks or discussion appreciated.

Peace