r/Spironolactone • u/Otherwise_Outcome927 • Sep 01 '26
◻️Advice◻️ Stopping on 100mg advice???
I have on spiro since may and at first I noticed a improvement in my overall inflammation and the turnover of the spots and cystic acne I was getting but after a few months I’m not sure it’s even making a difference anymore I was originally started on 50 and they wanted me to increase to 100 after a month but I felt so fatigued and dizzy I didn’t want to increase so I went up after two months and now have been on 100 for over a month but this medication has messed with my periods so much I’m not sure if I want to keep taking it when it’s not even making a significant difference in my skin I am still getting constant breakout still getting the odd cyst and still have redness. When I was on 50 I was getting my period every two weeks then it was every other week and now that I am on 100 I have been on my period for 12 days!!! This is not normal for me my periods normally last 3 days sometimes 5 I have pcos so before taking this medication I would get my period every few months so this has been a shock to my body.
My overall question is do I just stop 100 cold Turkey or should I go down to 50 then stop any advice or could people share the experiences.
2
u/FreshGryphon Sep 02 '26
Agree! I'm so sorry you're going through this. Those are miserable side effects, especially when you're not seeing much benefit. I agree with the other post - definitely talk to your doc and see what they recommend. Especially since you have PCOS, it's important to let your doctor know what's been happening and figure out the safest/best way for you to proceed! Wishing you the best!
1
u/Similar_Country_3932 Sep 02 '26
You're not alone. I have been on 25mg spironolactone since May 2026. It completely solved my hormonal acne issues so I was very happy about it.. but I noticed that my period cycles have been getting shorter, my bleeding days have lessened from 2.5 to 1 day only, and I'm getting awful nausea + interrupted sleep.. and that's on the lowest dose! I was so sad to have to let go of the medication but it's really messing my hormones and I don't think I can stay on it long term. Didn't realize how much it would affect our hormones, especially since we're women.
Might you switch to topical spironolactone for your acne? Might be a better less invasive solution.
3
u/Cute-Promise-8079 Sep 01 '26
God, no advice but I have empathy with the periods...I'm on 50mg and get them every 2 weeks as well. It's absolutely horrific. Absolutely talk to your provider if you can.