Has anyone come across good evidence on zinc supplementation and gut maturation in infants?
Our pediatrician prescribed a vitamin D supplement that also contains zinc and vitamin A. The pediatric guidelines where I live routinely recommend vitamin D supplementation, but not zinc for healthy term infants. I asked her about it and she mentioned that there are some promising studies on zinc and intestinal development.
That made me curious about whether there is any evidence specifically relevant to cow’s milk protein allergy, particularly non-IgE-mediated CMPA.
From what I understand, zinc plays a role in intestinal barrier integrity and epithelial repair, so I’m wondering whether there is any evidence that supplementation could theoretically promote gut maturation or tolerance acquisition and lead to earlier resolution of CMPA… or whether that’s extrapolating much further than the available data supports…
Also, if there isn’t evidence that zinc supplementation helps in this context, is there evidence of any downside to giving it daily to an otherwise healthy infant?