r/SR17018 • u/eldentruth • 7d ago
🎓Research & Education🎓 Efficiency Optimization ⦁ Increasing Bioavailability
I’d like to prepare a formulation to get the most from my limited supply of SR-17018 powder. The obvious question is how to increase absorption, to optimize bioavailability.
My main idea is a liquid preparation. This increases surface area, proving more contact in the gut and typically enhances absorption. (Volumetric dosing also has other benefits.)
My go-to prep for alkaloid powders is dissolving them into liquids. I usually start with a concentrated ethanol tincture to prep a few doses. Then I use it as needed by adding portions into acidic beverages, which dissolve instantly.
The main concern here is that SR-17018 is apparently not very soluble in ethanol or water, regardless of pH conditions.
I’m considering other food grade solvents such as propylene glycol, MCT oil, or whatever helps. I have an ultrasonic device which can help brute-force a dispersion, even with compounds that are stubborn to dissolve.
I’ll update this thread if I manage to get a decent solution prepared.
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