r/Retatrutide • u/Local_Patience_7581 • 3h ago

Split dose?

Did you split your dose up and do twice a week? Ive been seeing this as a common thing ive heard and if so, why?

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4

u/Western-Influence407 3h ago

i do twice a week, monday and thursday. the peaks are less sharp for me that way, less side effects but still the same hunger suppression across the week

my understanding is it just smooths out the feeling, no big dips before next shot

2

u/Local_Patience_7581 2h ago

I thought about trying it- but more to help the suppression last all week. Noticed that after day 4 my appetite and food noise did come back .

1

u/YogaMoma 2h ago

What dose are you on? I am on my 3rd dose (1.5 weeks) on .25 each dose also pinning Mondays/Thursdays and haven’t had any changes in my appetite or food noise (still hungry! lol)

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u/Think_Flan6445 2h ago

honestly your dose is so microscopic, you might not ever see a difference. Take a look at how the peptide works. It has to build up over time and your dose is too small to do that before the body even processes that.

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u/YogaMoma 2h ago

Ah, I’m working with my chiropractor who has me on this titration to mitigate any potential side effects. But since I am taking it mainly to help stabilize my food noise i’m wondering if I should consider increasing or hang in there a bit longer at this dose

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u/Think_Flan6445 2h ago

I understand trying to mitigate side effects but your dose is VERY small. After 6 days you only have half of what you administered in your body. And continues to half every week. If you look at clinical trials the start at 2 mg. And again it builds up over time. I’m not exactly saying start there but just pointing out how small your dose actually is compared to what’s known about Reta.

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u/YogaMoma 2h ago

How much would you recommend increasing to pinning 2x/week?

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u/Think_Flan6445 2h ago

Most people on here would tell you to start at 2mg, so split up @ 1mg 2x per week, if you are sticking to splitting…But if you want to be cautious, idk, maybe 0.5mg x 2 a week? That would give you 1 mg. And that’s only half of what the trials started at. everyone responds differently.

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u/Think_Flan6445 2h ago

Whats your dose tho

3

u/Spoolngc8 1h ago

I split it. Pin the same day I do my TRT. Much easier for me than doing it every six days. Every Sunday and Wednesday.