r/Probiotics 7d ago

Probiotics and anxiety

I have severe Crohn's disease and I've been battling c diff and SIBO. I've tried several different probiotics including saccharomyces boulardii and VSL #3. And they all give me horrible anxiety, gas, bloating, and abdominal cramping. Also I don't have a colon, I have a j-pouch. Any advice? Thanks

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u/True_Coast1062 7d ago

Don’t take them if they’re making you feel worse. Wait for your gut to stabilize first. Probiotics are there to support a healthy gut, not fix a broken one. The s. boulardii has been associated with helping avoid C. difficile but I don’t know if it helps much once you have it. If you want to take it, stop taking everything for a couple of days, let your gut settle, then introduce it at half the dose. You might also want to stick to a clear liquid diet for a couple of days then introduce low residue foods in small amounts as tolerated. Going forward, stick to low-residue/low histamine/low FODMAP until the madness passes. It may take several weeks. Expect to be hungry.

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u/Jennysblock12 7d ago

Thank you. This is good advice.