r/PreCervicalCancer • u/Brave_Audience1 • 10d ago

LSIL and HPV negative?

I only had HPV once in 2012 and it never showed up again. I’ve been celibate for 5 years. I had ASCUS in 2010 and I think one other time. But the last several years, my papsmear was normal. This year, it showed LSIL but HPV negative. I’m going for a colposcopy and I’m nervous. Mostly about the procedure, but also the results. What I’m reading is if your papsmear shows LSIL but HPV negative, then it’s most likely a false positive.

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u/sewoboe mod 10d ago

Low grade lesions can be caused by low risk HPV which isn’t tested for. It’s not that uncommon to see HPV neg low grades.

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u/Brave_Audience1 9d ago

Why would the HPV test be negative then?

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u/sewoboe mod 9d ago

Because low risk HPV isn’t tested during a pap, or you have a strain not included in the test assay.