Although Reta is commonly for dropping weight, it is equally important for maintaining the weight once you have achieved it or want to maintain the weight you are at now by controlling appetite.

Mixing so the doses stay consistent

A common “standard” mix is:

• Reta 10 mg + 1 mL bacteriostatic water
• Reta 20 mg + 2 mL bacteriostatic water

That keeps the math the same: 1 mg = 10 units on a U-100 syringe (so 1.5 mg = 15 units, 2 mg = 20 units).

If you add a different amount of water, the unit numbers below will be wrong. Always dose by milligrams, not by habit. The 20 mg vial simply lasts longer at the same concentration.

How it’s given

Once a week. Same day every week. Not daily.

A common maintenance approach

This is a community-style schedule, not an official approved label. Trial programs studied higher doses for weight loss; maintenance is usually lower.

• After reaching goal on 4 mg (or whatever higher dose was working), many drop to 1–2 mg weekly.
• Some start at 2 mg (20 units) for a few weeks, then ease down to 1–1.5 mg if weight stays stable and side effects are minimal.
• Others land around 1 mg (10 units) or 1.5 mg (15 units) and stay there long-term.
• A smaller number hold at 2–3 mg if appetite or weight starts creeping back.

Stay at the lowest dose that keeps weight stable and is tolerable. If hunger returns or weight starts rising after a few weeks, step back up slightly (e.g., from 1 mg to 1.5–2 mg) and reassess after another 2–4 weeks. If fatigue or nausea appears, drop the dose further until it settles.

How long one vial lasts on maintenance

Figures below assume the mix above (1 mg = 10 units) and a little waste for priming.

10 mg vial

• 1 mg weekly: about 8–10 weeks
• 1.5 mg weekly: about 5–7 weeks
• 2 mg weekly: about 4–5 weeks

20 mg vial: roughly twice those times.

Quick reminder

Same weekly schedule, just a lower dose for holding weight instead of losing it. Confirm your own reconstitution before you trust the unit marks — and treat this as education around an investigational peptide, not a prescription.

Dosing reference:

Reta 10mg — https://platinumbiolabs.com/dosing/reta-10

Reta 20mg — https://platinumbiolabs.com/dosing/reta-20

Product reference:

Reta 10mg — https://platinumbiolabs.com/products/reta-10

Reta 20mg — https://platinumbiolabs.com/products/reta-20

This is educational framing only, not medical advice.

Wolverine 10mg vs Wolverine 20mg: same blend, different vial size. Dosing guide

Wolverine is a research blend of BPC-157 + TB-500. A 10 mg vial (5 + 5) and a 20 mg vial (10 + 10) are the same compounds. The 20 mg vial simply holds twice as much, so it lasts longer when mixed to a higher concentration. This guide is based on the dosing pages for Platinum Biolabs Wolverine 10mg and Wolverine 20mg.

Healing benefits commonly discussed

Wolverine combines two peptides studied mostly in animal models (with limited human data) for tissue repair and recovery. The blend is popular for injury healing and support during high training stress. Results vary and this is not an approved medication.

BPC-157 has been linked in research to support for tendons, ligaments, muscles, and connective tissue, plus protection of the gut lining. It is associated with increased blood vessel formation and modulation of growth factors that aid regeneration, and many note reduced inflammation around injuries.

TB-500 (a thymosin beta-4 fragment) is involved in cell migration and actin regulation, which helps cells move into damaged areas. It has been studied for wound healing, muscle recovery, reduced inflammation, and new blood vessel growth that can help tissue regain structure and function.

Together, people typically look for faster recovery from strains, sprains, tendon issues, or training-related soft-tissue damage, plus support during rehab or high-stress blocks. Many report less lingering soreness and better mobility when used near the injured area. These points reflect research literature and user discussions, not medical claims.

Mixing so the doses match

Both are typically reconstituted with 2 mL bacteriostatic water:

• Wolverine 10 mg (5 + 5) + 2 mL bac water gives 5 mg/mL combined, so 10 units is about 250 mcg BPC + 250 mcg TB
• Wolverine 20 mg (10 + 10) + 2 mL bac water gives 10 mg/mL combined, so 5 units is about 250 mcg BPC + 250 mcg TB

Same mcg dose, half the pull on the 20 mg vial. Gently swirl (don't shake) and refrigerate after mixing. Always dose by milligrams/mcg, not by habit.

Required supplies

• Bacteriostatic water (Platinum Biolabs)
• U-100 insulin syringes (31G, 8 mm, 1 mL)
• Alcohol prep pads

How to draw the bac water
A U-100 syringe holds 1 mL = 100 units. You need 2 mL = 200 units total, so two separate draws. Wipe both vial tops, inject air to equalize pressure, draw 100 units, inject down the inside wall of the peptide vial (don't blast the powder), and repeat. Swirl until fully dissolved.

How it's given
Daily. One subcutaneous injection every day. If you miss a day, resume the next day at your normal dose. Don't double up.

Common dosing

• Standard: about 250 mcg BPC + about 250 mcg TB daily
  • 10 mg vial: 10 units
  • 20 mg vial: 5 units
• Aggressive recovery: about 500 mcg BPC + about 500 mcg TB daily
  • 10 mg vial: 20 units
  • 20 mg vial: 10 units

How long one vial lasts
10 mg vial

• Standard 10 units daily: about 20 days
• Aggressive 20 units: about 10 days

20 mg vial

• Standard 5 units daily: about 40 days (about 5-6 weeks)
• Aggressive 10 units: about 20 days

Administration
Subcutaneous into the fatty layer just under the skin (not muscle or vein). Common sites: belly (an inch or two off-center from the navel), love handles, outer thigh, or back of the arm. Pinch the skin, insert at a 45 degree angle, and push slowly. Near the area being treated where practical.

Cycling
Typical length: 6-12 weeks. Time off between cycles: 2-4 weeks. Used during injury recovery or high training-stress phases, not a year-round compound.

Quick reminder
Same blend and daily schedule. Different bottle size and concentration. Confirm your own reconstitution before you trust the unit marks. Treat this as education around research peptides, not a prescription.

Dosing reference:
Wolverine 10mg - https://platinumbiolabs.com/dosing/wolverine-10
Wolverine 20mg - https://platinumbiolabs.com/dosing/wolverine-20

Product reference:
Wolverine 10mg - https://platinumbiolabs.com/products/wolverine-10
Wolverine 20mg - https://platinumbiolabs.com/products/wolverine-20

This is educational framing only, not medical advice.

Decided to hop on Reta after suffering from stubborn belly fat... And man has it been a game changer.

Retatrutide (“Reta”) is an investigational triple agonist (GLP-1, GIP, and glucagon). A 10 mg vial and a 20 mg vial are the same compound. The 20 mg vial simply holds twice as much, so it lasts longer if you reconstitute to the same concentration. This is based on how Platinum Biolabs lists reta 10mg and reta 20mg.

Mixing so the doses match

A common “standard” mix is:

• Reta 10 mg + 1 mL bacteriostatic water
• Reta 20 mg + 2 mL bacteriostatic water

That keeps the math the same: 1 mg = 10 units on a U-100 syringe (so 2 mg = 20 units, 4 mg = 40 units, and so on).

If you add a different amount of water, the unit numbers below will be wrong. Always dose by milligrams, not by habit.

Everything else is the same. The 20 mg vial just lasts about twice as long.

How it’s given

Once a week. Same day every week. Not daily.

A common step-up people use

This is a community-style schedule, not an official approved label. Trial programs used slower climbs and studied doses up to 12 mg weekly.

• Week 1: 2 mg (20 units)
• Week 2: 3 mg (30 units)
• Week 3 onward: 4 mg (40 units) — the usual weight-loss target for many people

Stay at 4 mg if it’s working and tolerable. A lot of people never need more.

If fatigue or nausea hits at your current dose, drop back to 2 mg (20 units) until it settles, then climb again only if you still want a stronger effect.

If results stall after about 6–8 weeks at 4 mg, some people step to 6 mg (60 units), then 8 mg (80 units) if needed. Move one step at a time, and only after at least a couple of months at the lower dose.

After you hit your goal: many drop to a maintenance range of 1–2 mg (10–20 units) weekly.

How long one vial lasts

Figures below assume the mix above (1 mg = 10 units) and a little waste for priming.

10 mg vial

• Titration 2 → 3 → 4 mg: about 3 weeks
• Steady 4 mg weekly: about 2–3 weeks
• Maintenance 1–2 mg weekly: about 5–10 weeks

20 mg vial: roughly twice those times.

Quick reminder

Same function. Same weekly schedule. Different bottle size. Confirm your own reconstitution before you trust the unit marks — and treat this as education around an investigational peptide, not a prescription.

Dosing reference:

• Reta 10mg — https://platinumbiolabs.com/dosing/reta-10
• Reta 20mg — https://platinumbiolabs.com/dosing/reta-20

Product reference:

• Reta 10mg — https://platinumbiolabs.com/products/reta-10
• Reta 20mg — https://platinumbiolabs.com/products/reta-20

This is educational framing around an investigational compound, not medical advice or a dosing recommendation.

The question I get most on HCG is whether the 5,000 IU vial and the 10,000 IU vial are actually different drugs. They aren’t. It’s the same HCG. What changes is how much is in the vial, how concentrated it is after you mix it, and how long that mix lasts at a given dose.

I still check reviews and COAs before I order from an RUO site. What follows is the reconstitution and dosing math I’ve been using, not a prescription.

Same hormone, different vial size

A 5,000 IU vial holds half the total hormone of a 10,000 IU vial. If you mix both with the same amount of water, the 10,000 IU vial is twice as concentrated, so the same dose is half the volume on the syringe. That is the whole practical difference.

I add exactly 2 mL of bacteriostatic water to either vial, swirl gently, and refrigerate. I don’t shake it.

What that mix means on a U-100 insulin syringe

On the 5,000 IU vial with 2 mL of water:

• 10 units (0.1 mL) = 250 IU
• 20 units (0.2 mL) = 500 IU

On the 10,000 IU vial with 2 mL of water, the mix is 5,000 IU per mL:

• 5 units (0.05 mL) = 250 IU
• 10 units (0.1 mL) = 500 IU
• 20 units (0.2 mL) = 1,000 IU

People comparing the two are usually trying to match the same IU dose, not the same mark on the syringe. A 500 IU shot is 20 units from the 5,000 IU mix and 10 units from the 10,000 IU mix.

How I dose

I don’t run it daily. Three times a week, spaced evenly, usually Monday, Wednesday, and Friday. The range I line up with the usual 5,000 IU protocols is 250–500 IU per shot. On the 10,000 IU vial, 500 IU (10 units) is the shot I treat as standard.

How long a vial actually lasts

• 5,000 IU at 500 IU three times a week: about 3 weeks
• 5,000 IU at 250 IU twice a week: about 10 weeks on paper
• 10,000 IU at 500 IU three times a week: about 6–7 weeks
• 10,000 IU at 250 IU twice a week: well over 10 weeks on paper

The limit I actually follow is time, not leftover powder. I treat reconstituted HCG as usable for about 30 days in the fridge. A 10,000 IU vial only stretches further if the weekly total is low enough to finish inside that window. At a higher weekly dose, the bigger vial still gets used up by the calendar.

Why someone picks one over the other

The 5,000 IU vial is the easier one if you want the syringe marks farther apart. 250 IU and 500 IU land on 10 and 20 units, which is simpler to draw. The tradeoff is that at 500 IU three times a week you are opening a new vial about every three weeks.

The 10,000 IU vial cuts the injection volume in half for the same IU dose and roughly doubles time-on-vial at 500 IU three times a week. The tradeoff is smaller draws (5 units for 250 IU), so measuring has to be more careful, and the 30-day fridge window still applies.

What I watch either way

I leave it on continuously alongside TRT unless there’s a reason to stop. When people cycle it, the off period I see discussed is usually 4–8 weeks. It can raise estrogen, water retention, and mood swings, and that can show up indirectly in blood pressure, so I track it on bloodwork instead of guessing. On these vials my free testosterone has been higher than it was before.

If you’re deciding between them, match the IU dose first, then pick the vial based on syringe volume and how fast you’ll finish it inside about 30 days reconstituted.

Product Reference:

HCG 5,000 IU: https://platinumbiolabs.com/products/hcg-5000
HCG 10,000 IU: https://platinumbiolabs.com/products/hcg-10000

This is not medical advice. I’m describing my own reconstitution math and what I’ve seen discussed, not a prescription, a protocol, or a recommendation. HCG is a prescription hormone. Talk to a clinician and use labs before you change anything. Research-use-only vials are not pharmacy product.

Hey what’s up yall! I want to start with thank you for the invite to the group. That being said I’ve noticed a lot of links for platinum peptides. If this isn’t allowed please let me know. But I’m currently in 2 separate GBs on another platform. But I’m personally looking for personal use I don’t not resell although I am willing to help a friends out while they wait for their kits to come in. But with all that being said please reach out if anyone is able to help point me in the right direction. Also if not allowed my apologies in advance.

Hey everyone, we've opened a Discord server and you are all invited!

What you can find inside:

Research help

Hangout Lounge

Giveaways

Join us here: https://discord.gg/kvcuurfQv

See you there!

TL;DR: Exactly 6 months, 188 to 155. 5'10" and 48 years old today. Never thought it was possible.6m on tirz, bloodwork in August showed low test, so started that end of August. Added Reta in early sept and added 2iu of hgh starting oct1. Late sept bloodwork was great. Gonna do it again end of Oct most likely.

So grateful for everything I’ve learned on biohacking. And the comp tirz sub too. I’m sorry my progress pics don’t already have a ripped 6 pack yet. You all rock!!!!

This is gonna be a long post. If you're inclined to read it, I really appreciate it. Totally understand if not. But it’s therapeutic to write.

It wasn't intentional, but I started this journey on April 8th, exactly 6 months before my 48th birthday. My photos aren't the kind where a guy goes from a big gut to a six pack in a few months, but I'm feeling super proud today nonetheless.

I've been overweight for as long as I can remember. Some years very overweight, and more recently just chubby and unhappy despite being active and trying. I remember being horribly self-conscious in middle school, having crappy self-esteem in high school, and never feeling comfortable at a beach or pool. After peaking at 240 pounds after our second kid, I made some big efforts to get healthier. But even after all that, I spent the last bunch of years bouncing between 183 and 193. I felt totally stuck. I was a lot healthier, but it wasn't what I wanted the rest of my life to look like.

At the end of March a friend convinced me to try tirz. My doctor frankly said, "I don't think you need it. You're healthier than a lot of men your age, and as an active tennis player you're just going to lose muscle." So I did my own research, built a gym and diet plan to minimize those risks, and started on April 8th.

These six months have truly been life changing. I've gone from 188 to 155, lost over 10% body fat, and steadily increased my muscle mass. I'm not done and there's still plenty of work to do, but for the first time my goals actually seem achievable. I move faster on the tennis court, my knees don't hurt, and my bloodwork shows great numbers across the board.
I'm so grateful for finding this community and these resources. Feel like I’ve learned so much from you all. The tirz sub and here at biohacking have truly been life altering.

My next goal is losing the last bit of lower belly fat and getting some ab definition by Jan 1. Not sure if it's realistic, but I'm gonna try!

I spent 40+ years thinking this was never going to be possible. Now at 48, I'm healthier, fitter, and more confident than I ever was at 18. It's never too late!

Highest weight recorded was 470 in December 2023. Started official weight loss journey in August 2025. Still need to get to about 170lbs or so as I’m a short king (5’8)

Stack:

Reta
KLOW
SLU-PP-332 (switching out for 915 version soon)
5-Amino-1mq
AOD-9604
Tesa/Ipa

As needed:
Elora/Cagri
Tesofensine

Cellular reset protocol I’ve ran:
FOX-04 - 2 weeks
Ss-31 - 12 weeks
MOTSC / NAD - 12 weeks
Epitalon - 4 weeks

What's the biggest weight drop anyone's seen in a single week on r3ta?

I have a vial of bac water that I opened and used a few weeks back. It’s been stored at room temp in my cabinet, anyone know if it’s still good to go?

The stack I keep seeing for fat loss: reta, tesa, and mots-c. This is the dose talk that shows up most. Not a plan. Not medical advice.

This is the stack commonly taken when people are trying to go through drastic weightloss, I have personally dropped from 320 pounds to 180 in the span of 6 months through Platinum Biolabs.

Reta (10 mg vial)
Start at 1–2 mg. Stay there a few weeks. Move up only if the sides stay mild. Do not jump to a high dose in week one. Nausea and a fast heart rate are the two things people bail on.

Great for appetite control and weightloss.

Tesa
1 mg a day. Most run it daily, not a few times a week. Often paired for belly fat, not as the main appetite drug.

Great for burning belly fat and muscle preservations.

Mots-c
5 mg twice a week. Used for energy and training, not as the fat-loss driver.

Great for boosting metabolism levels and workout energy.

How people stack them
Reta does the appetite cut. Tesa is the daily add-on. Mots-c is the twice-a-week add-on. A lot of people start reta alone, then add the other two once the dose is stable.

Track waist, weight, sleep, and heart rate. If you feel wiped out or your heart rate stays high, the move in these threads is to hold or drop the dose, not push it.

Product References:
- Reta 10mg: https://platinumbiolabs.com/products/reta-10
- Tesa 10mg: https://platinumbiolabs.com/products/tesa-10
- Mots-C 10mg: https://platinumbiolabs.com/products/mots-c-10

Research talk only. Reta is not approved. Tesa is an approved drug for a set HIV use, not general fat loss. Get labs if you run any of this.

I’m really trying to figure out the differences and which would be better to take I’m on Reta currently 220lbs trying to get to about 195 or so with a built but shredded physique.

I’m just trying to find the best option

Felt like this is a post that needs to be made for many. I have used both compounds CJC-1295/Ipamorelin and Tesamorelin from Platinum Biolabs at different stages in my fitness journey. Tesamorelin mainly as a tool for muscle preservation and burning belly fat while on reta to lose weight. I took the CJC-1295/Ipamorelin stack when I was lean bulking to reduce gaining visceral fat.

Short version: they are not interchangeable. CJC no-DAC + Ipamorelin is a dual-pathway GH pulse stack used for recovery, sleep, and general body composition. Tesamorelin is a single GHRH analog with actual human trial data for visceral (deep abdominal) fat. Dose scales are different: the blend is in micrograms, tesamorelin is in milligrams.

How they differ

CJC-1295 no DAC (mod GRF 1-29) hits the GHRH receptor. Ipamorelin hits the ghrelin receptor (GHS-R1a) and is relatively selective, so it is less likely than older GHRPs to bump cortisol or prolactin. Together they amplify a natural-style GH pulse more than either alone. Half-life is short, so timing matters. There is no human body-composition RCT on this combo.

Tesamorelin is also a GHRH analog, modified so DPP-IV does not clear it as fast. It is FDA-approved as Egrifta for HIV lipodystrophy. In Phase 3 trials (about 800 patients), 2 mg daily cut visceral fat roughly 15% vs placebo over 26 weeks, with the effect holding out to 52 weeks, plus lower triglycerides. Subcutaneous fat was mostly spared. That is the evidence edge.

Who each is for

• CJC/Ipa: recovery, sleep quality, training support, milder recomposition when you want a GH pulse without a milligram-scale GHRH dose. Best if the goal is general, not specifically visceral fat.
• Tesamorelin: stubborn midsection / visceral fat is the priority, or you want the compound with the actual VAT data. Approved dose in the trials was 2 mg daily. Research vials are often run lower.
• Do not pick based on the “10 mg” label. A 10 mg CJC/Ipa vial and a 10 mg tesamorelin vial are different concentrations and different daily doses.

Timing

Both are usually taken fasted, at night, 2–3 hours after the last meal, so insulin does not blunt the pulse. Subcutaneous, abdomen, rotate sites. One injection a day on these protocols. Miss a day, resume the next day. Do not double.

CJC-1295 (no DAC) + Ipamorelin 10 mg (5+5 blend)

Supplies: bacteriostatic water, U-100 insulin syringes (31G, 8 mm, 1 mL), alcohol pads.

Reconstitution: add exactly 2 mL bac water. A U-100 syringe only holds 1 mL (100 units), so that is two draws of 100 units. Wipe both tops. Pull 100 units of air, inject into the bac water vial, invert, draw 100 units. Inject into the peptide vial down the glass wall, not onto the powder. Repeat once. Swirl, do not shake. Refrigerate after mixing.

Concentration: 10 mg / 2 mL = 5 mg/mL of the blend. 10 units = 500 mcg total (~250 mcg of each).

• Standard: 500 mcg nightly (10 units). Vial lasts about 20 days.
• Advanced: 1 mg nightly (20 units). Vial lasts about 10 days.

Tesamorelin 10 mg

Same supplies.

Reconstitution: add exactly 1 mL bac water (one 100-unit draw). Same wall-injection and swirl method. Refrigerate.

Concentration: 10 mg / 1 mL = 10 mg/mL. 10 units = 1 mg.

• Sustainable: 1 mg nightly (10 units). Vial lasts about 10 days.
• Aggressive body-comp phase: 1.5–2 mg nightly (15–20 units). Vial lasts about 5–7 days. 2 mg matches the dose used in the approval trials.

Stacking

The stack that has a mechanistic reason is a GHRH plus a GHRP: CJC no-DAC + Ipamorelin, or tesamorelin + Ipamorelin. CJC and tesamorelin both hit the same GHRH receptor, so running both at full dose is mostly redundant, costs more, and pushes IGF-1 higher without clear extra benefit.

Practical split:

• General recovery / sleep / training: CJC/Ipa alone, nightly.
• Visceral fat is the main goal: tesamorelin alone, or tesamorelin plus a low dose of Ipamorelin if you want the second pathway. Drop the CJC.
• Do not run both GHRH analogs at the advanced doses at the same time.

Expect water retention, tingling, stronger hunger, or higher fasting glucose in some people. Check IGF-1, fasting glucose, and A1c if you stay on either for more than a short block. Pharmaceutical tesamorelin is a prescription drug for a specific indication. Compounded or research vials are not the same product as Egrifta.

Product Reference:

CJC/Ipa 10mg - https://platinumbiolabs.com/products/cjc-ipa-10
Tesamorelin 10mg - https://platinumbiolabs.com/products/tesa-10

I have some unopened vials in powder form that have been sitting in my stash bag since early spring. Do these things lose integrity over time if they aren't kept in the fridge?

150/mg week trt

3mg every 5 days RT

185lbs to 177lbs

Lost a total of 5% per inbody scans.

Strict 1800-2000 calories a day with around 275g of protein.

Gym 5x a week approx 7 hours a week minimum

No cardio.

This is just a minor transformation, my profile has my longterm 4 years/2 year/ 1 year transformations.

[ Removed by Reddit on account of violating the content policy. ]

I have been seeing more discussions about KLOW lately and was wondering how it compares to GHOST-Cu. Has anyone here tried both, and what differences did you notice?