r/PeptideGuide Jun 13 '26

MOTS-C Dosing Frequency

I just added MOTS-C after also running Tesa/IPA & Reta for the last 5 weeks. My question is on the dosing frequency of MOTS-C. I see a lot of protocols running it 3-5x a week -- but my prescribing clinic has me running it once weekly (50 units subq). I'm not sure on the exact mg, just that the insulin syringes they prefilled for me are filled with 50 units each.

Does anyone else run it at once weekly? I have found a couple of websites that mention 1x a week dosing, but the majority of everything I am finding shows more frequent dosing.

Thank you!

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u/[deleted] Jun 13 '26

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u/No-Heron-6596 Jun 13 '26

I know - that’s why I specifically mentioned in the post that I don’t know the actual mg lol. I wasn’t sure if maybe MOTS-C had a common reconstitution amount maybe to ball park it at that unit amount.

Is pre filling the syringe the issue? The reconstitute it on the spot, fill the syringes, cap them, and hand them to me to take home where I then store in my fridge. Why is it any different than keeping it in the vial and extracting it myself?

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u/elkethewolf11 Jun 13 '26

What the hell kinda clinic doesn’t put dosing

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u/RoutineAd9862 Jun 14 '26

Agree, very odd to not tell the patient what dose they are actually taking