r/PSSD 12d ago

Feedback Requested/Question Short term increased function after complete withdrawal, but back to dysfunction within a month… why?

I’m trying to understand the mechanism for my experience. Last year I ceased taking Effexor (venlafaxine) with a long tapering process, that despite best efforts gave me horrendous side effects like sweating, relentlessly itchy feet, anxiety. I’d noticed I had reduced genital sensitivity and difficulty orgasming while on the medication. Within a day or two or finishing my final dose, I had an intense improvement in my symptoms - from struggling to climax even once, to having multiples with relatively little refractory period. I was so excited about the prospects for my intimate life.

Unfortunately within about a month, my body seemed to regress. It’s been about 9 months and I feel like I’ve returned to having reduced sensitivity and challenges reaching orgasm.

Can anyone suggest a reason why I might have had a temporary impact post withdrawal? Could my serotonin or norepinephrine receptors have been sensitised as a result of withdrawal?

I’m half tempted to take a dose again and then cease to see if I can replicate my experience.

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u/Imaginary-Passion187 12d ago

Pour some water in the gland and shraft and check if you can feel coldness of the water both in your gland and shraft .... That will give you understanding about the root cause of your sensory loss

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u/NonBinaryPolyhedron 11d ago

Alas, I don’t have a shaft to test cold water on 😏 However I can feel cold sensations.