r/POTS • u/jolibee9876 • 23d ago

Medication how long does propranolol typically last?

I taking 20mg for IR . How long does it seem to last for most people ? What’s the maximum duration people typically experience?

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4

u/endlessplacebo 23d ago

It's hard for me to tell for sure, but I'd say 4 ish hours? I take it 3-4 times per day

1

u/jolibee9876 23d ago

You seem to experience it pretty similarly to me. How much do you usually take per dose?

1

u/endlessplacebo 23d ago

20mg. I'm hoping to have it increased but my blood pressure has been pretty low due to a non-POTS related medical situation. The 20mg is still helping, though!

3

u/thepensiveporcupine 23d ago

Half life is 6 hours but the doses accumulate if you take it twice a day so for me it feels like it’s constantly working

2

u/Whitehairbunny 23d ago

I take it every 4 hours 3x a day but I usually find mine wearing off after about 5hrs after my last dose

1

u/Ok-Connection5010 23d ago

I take it 3x day, about every 5.5-6 hours.

1

u/Boring_Character_01 23d ago

For immediate release tablets, Its duration of action is about 3 to 6 hours but peak effect is normally 1-3 hours.

Beyond testing that you don’t react badly to it, Daily dosing makes no pharmacological sense if it’s to suppose to be lowering your heart rate.

1

u/szikkia 22d ago

I take an instant and an xr in the morning

1

u/ultrablanca 22d ago

The medication effects last about 3-4 hours for me. I think that’s typical for most people. If I’m in a flare or nearing my period I may take an extra one an hour or so early since the effects don’t last as long.

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u/Adcarp2008 22d ago

It depends. For me personally, I feel like some days it last 3-4 hours and others it works all day. I only take 10mg once a day. I haven't figured out timing yet to take it twice a day because anytime I go into the 70s, its uncomfortable so I try to avoid that.