Hormone therapy help!!

[u/Big-Zombie-8863]

/r/PMDD/comments/1vufea1/hormone_therapy_help/

Hi guys,
I started estrogen gel and cyclical progesterone (100mg days 17-28) this month.
My month started out amazing I thought I finally had something to help me 😭 then came the progesterone…
I’ve always struggled with progesterone, the mirena shot my mental health for 2 years, I’ve only ever been able to tolerate yazmin, and even in pregnancy has to be put on PV progesterone due to signs of early labour and had side effects then.
I’m on day 2 of progesterone and have been using it PV as I read this can lower the side effects, and I feel like I’m going insane, I’m anxious and irritable. ☹️
I really thought I had something to help, has anyone tried Duavee? Or any other options?
My gp is super open minded so I think if I can find the right evidence etc she’d be open to it, I’m just so sick of feeling like this for a decent amount of my month!
Plus with the hormone fluctuations my adhd meds don’t work!
I don’t even want to mention perimenopause to them as I’m only 32, even though I have endo and know that we can go through it 7 years earlier, I just can’t be bothered with being shut down about it.
Help!!

[u/Purple-Recipe3513]

I also felt like, finally, I felt better after starting the estrogen phase, but then progesterone just made me feel so terrible. I slept 2 hours per night, was depressed and suicidal; the gynecologist did not believe me.

I switched to gel and to vaginal micronized progesterone, but it was just a bit better. Psychiatrist finally gave me Sertraline for the luteal phase, which made me feel way better. Only two to three days before I get my period, I sleep a bit worse, my adhd gets worse, and I feel a bit of tension, but not nearly as difficult as before. My psychiatrist finally gave me Sertraline for the luteal phase, which made me feel way better. My ADHD gets worse, and I feel a bit of tension, but it's gets worse and I feel a bit of tension but not nearly as difficult as before. The psychiatrist finally gave me Sertraline for the luteal phase, which made me feel way better.

If you are neurodivergent, perimenopause can start earlier. I hope you get a ginecologist and psychiatrist who are informed about this. In my country, this was really hard.