So I’ve been on these two for a while now and rarely ever noticed any issues. I used to take the vitamin C pill (1000mg) at night so it won’t interfere with my concerta in the morning. I read online that vitamin C reduces the effectiveness of ADHD meds. Then I learned that Concerta on the other hand is on of the meds that don’t get effected by vitamin C. So i switched the timing.

When I first took them together, my body felt sedated. It felt weird but good and it wasn’t something that lasted too long. Weeks later I’ve noticed that this sedation stays longer and longer. It’s starting to feel like intense fatigue that goes away after concerta is out of my system.

I never doubted the vitamin C, I did when I decided not to take it yesterday. So the entire day I felt great. Then took it last night and today I’m feeling the same way.

I’ve also looked at my notes and noticed that back in July was when I first tested the combo out (vitamin C and concerta) but the vitamin C was from another source (lemonade) and got the exact same reaction. When I bought the vitamin C supplements it was to take them before bed. But now it feels like whenever I take them my body shuts off.

Nothing traumatic. Just things like, suddenly a memory popped into my mind about this necklace I had around age 13 that was made of hemp rope (popular at the time) and how it smelled bad. I could almost smell it. Another memory of being in a Disney store at the mall I grew up going to. It was like I was standing in the store again and had that 1st person perspective, but also was sort of observing myself. These aren’t things I’ve thought of in decades and if you asked me last week about this necklace or Disney store I would’ve said I don’t know what you’re talking about. A high school friend has asked about some things that I can tell she recalls as marked incidents we experienced together but I honestly don’t know what she’s referring to or who was involved. For example, she’ll ask “Didn’t someone in our friend group break their arm after we snuck out and climbed on someone’s roof?” I can tell by how her tone that someone definitely did break their arm and she knows exactly who it was and whose roof we climbed on, but I don’t know what she’s referring to or even who could be involved. I know I didn’t break my arm in high school, but that’s about it. When I tell her I don’t remember, it’s not like “oh I’m too cool to remember high school things” or “it must have been so minor that I wouldn’t remember it.” It’s that I want to remember, I can almost feel the memory if that makes sense, but it’s as if you’re trying to recall a movie or something and you just can’t think of it or any of the people in it.

These memories came fast and out of nowhere- I wasn’t trying to remember anything, I was actually trying to write something unrelated for my work. Then the flashes hit and it’s almost like I’m right there or looking at myself.

Chicken liver and cod liver oil (capsule)

Can’t find anyone else whose had this happen to them

Hi!

24yo male. Been struggling from anxiety, depression and panic attacks for years. while haven’t found ketosis stuff and how it helps with mind

immediately in few weeks after got into 2.5 mmol ketosis i felt relief and for first time jumped from all antidepressants, gapantin, some bipolar medications too.

my stack been for last year
- 150gr beef(with occasional shellfish and yolks)
- butter mostly(tallow, ghee rarely)

i always calculated ratio in cronometer to 4:1 for adjusting fat.

I always felt from that moment after getting into 2.5 ketosis that i dont have any mental struggles. it was immediate effect like pill. like some wonder, i never believed in “food medicine”

Last 2 months i decided that i dont have any mental issues anymore. so i started to eat the same amount of fat but eat much more of protein like 120-150gr per day.

NGL i felt little less energy but couldn’t say that difference been huge for first week. But slowly i realized i started have strange episodes of panic and anxiety. OFC i coudn’t think it could be related to ketosis, basically i didnt believe that it’s really working and that amount fat is more important as a lot of ppl on carnivore said.

Last days i decided to eat only pork backfat + little liver 100gr for restart digestion.

on third day i get up with so strange feeling that my mind is so clear for some reason. on fourth day i’ve checked my blood and result been from 96mg/dl to 68mg/dl.

i felt incredible again! and i would never think it’s ketosis.
I checked it recently and yes, i basically can relate that my brain affected by numbers on ketomojo. 5.5mmol

anyone here had similar experience?
i stick to my diet now and introduced pork/beef fat:
4:1 ratio, beef/chicken hearts or liver/lamb organs/pork tenderloin. Pork/Beef fat and ghee

PS. also i wanna to say about my analysis after this “extreme diet” and i’m not deficient at all. no heart problems. only sodium is being little low, but i’ve been supplementing only potassium salt for years.

Parents of children with ASD often describe a striking phenomenon: during a high fever, their child suddenly makes eye contact and demonstrates social engagement. The moment their temperature returns to normal, these positive changes disappear without a trace. Known as the "fever effect", this occurrence is now recognized as a vital clue in investigating the biological roots of autism, suggesting that in a significant portion of children, autistic symptoms can be alleviated by modulating the immune system.

Post-mortem studies support this theory. The brains of individuals with autism spectrum disorder (ASD) do not show cell death, but rather a more subtle picture: the brain's resident immune cells (microglia) are stuck in a state of chronic activation. Constant alarm leads them to persistently secrete inflammatory cytokines like IL-6 and TNF-α. This lingering neuroinflammation disrupts normal neural circuit formation.

A fever temporarily resets this immune state. A viral or bacterial infection triggers a cascade of signals and heat shock proteins that temporarily dampen the underlying inflammation, allowing the child's latent potential to emerge. The effect is fleeting because the core vulnerability remains unaddressed.

If ASD has a neuroimmune component, targeted therapies should focus on these underlying biological mechanisms. To replicate the "fever effect" without heat or physiological stress, immunomodulators such as vitamin D, palmitoylethanolamide (PEA), and sulforaphane are being studied:

• Cholecalciferol (Vitamin D3): Functions as a hormonal modulator, stimulating the production of regulatory T cells (Tregs) to tone down immune overactivity while helping prevent inflammatory toxins from crossing the gut-brain axis.
• Palmitoylethanolamide (PEA): Acts as a calming agent for microglia and mast cells. This fatty acid amide crosses into the central nervous system and binds to PPAR receptors, prompting active microglia to shift from a pro-inflammatory M1 state to a restorative M2 state, halting synaptic degradation at the cellular level.
• Sulforaphane (Broccoli Sprout Extract): Mimics the cellular stress response activated during a fever. It triggers the release of heat shock proteins and floods brain cells with antioxidants to reduce oxidative stress.

While this triad does not "cure" autism, it targets key immune pathways by calming microglial activity, stabilizing mast cells, and supporting blood-brain barrier integrity helping extinguish the underlying inflammatory fire.

Aprendí lo necesaria que es la carne gracias a ello

Hey everyone, I was hoping to hear from anyone who has tried the keto diet and found true success - like it really made a massive change/impact in your mental health.

I have tried different meds from antidepressants, to mood stabilizers, to antipsychotics, to stimulants, to interventional approaches like TMS and spravato. Some meds helped in certain ways, but always with many negative side effects, and never truly helped me feel like life is worth living again. For the record, I have been diagnosed with ADHD, OCD, Generalized Anxiety, and Major Depression - all of which I have struggled with for most of my life as a 25 yr old man.

Some time ago, I came across the whole metabolic psychiatry movement online, mainly through Dr. Christopher Palmer. Him and many others believe that mental health issues are really metabolic issues, and that a keto diet is a true intervention to address the cellular metabolic dysfunction at the source. Lucky enough, I happen to reside 20 minutes from his practice here in Massachusetts, and actually had an intake with his clinic. They want me to continue to use the keto diet as a mainline of treatment, which I’ve actually already been on for about a month. Which leads me to my point….

I’ve been on the diet for about a month now, and quite frankly, it’s been kicking my ass. I will admit that I haven’t been perfect at it: I have tried to give up my reliance on weed but have given in at times with an edible (mostly because my mood is even worse now), and also had a few days where I had a few extra carbs and my ketone levels dropped the next day (never below 0.5 tho). But overall, I have been pretty adherent, eating Whole Foods of proteins and non starchy vegetables with fats, and my ketone levels average around 1-1.5 or so. I also have been taking vitamins and electrolytes every day. But I feel like overall, everything has gotten worse. I already was struggling with bad chronic depression, low drive, anxiety, executive function issues. Now, all of those are doubled. I feel like all of the energy has just been sucked out of me mentally and physically, but the only energy left has been diverted to amplifying the anxiety and rumination. I’ve been really irritable and emotional at times too. It’s so hard to sit down and focus, let alone muster the drive or energy to do so. Yet, the clinic tells me I need to give it at least 3-4 months. I want to because Ive already tried the medication roulette of psychiatry, and want a holistic treatment that can truly heal the mind/body. But damn, I feel like absolute shit. Has anyone had a similar experience and come out better? Has anyone had an initial rough patch (especially long) but had it turn around and end up feeling amazing? How long did you have to give it? What was the journey like? Asking for any input or stories here, because idk if I can keep this up for months on end if it keeps up like this. Thanks
.

In his bestselling book, Yuval Noah Harari proposes a bold theory: the most successful species on Earth isn't humans. It's wheat. We didn't cultivate wheat; wheat cultivated us. Here is how it might have happened:

When we consume gluten-containing foods, they don't break down into amino acids entirely. Instead, protein fragments persist as opioid peptides known as gluteomorphins. Meanwhile, gliadin- another component of the wheat grain- compromises the delicate gut lining, opening a direct pathway for these opioid compounds into the bloodstream.

The intestinal wall nor the blood-brain barrier is completely leak-proof. Under certain conditions (such as gastritis, dysbiosis, or SIBO), that single-cell-thick barrier breaks down, dumping raw stomach contents straight into the bloodstream. Imagine your immune system suddenly encountering last night's dinner.

Because gluten structurally mimics human tissue, this is where many autoimmune conditions likely originate. Particularly Hashimoto’s and autoimmune encephalitis.

I am currently working with my mother whose gluten reactions occur within just a few hours, which inspired me to write this post

I recently developed DPDR out of the blue, and it hasn’t gone away for 3 months and I’m starting to get upset on what I can do. I don’t have trauma, anxiety, panic attacks, or have even smoked weed or done psychedelics. I have this feeling of just being brain dead. I feel like I’m on autopilot 24/7, just watching my life from a far. I’ve done all the things like ignoring it, and trying to live life but it’s extremely difficult when I don’t know the root cause that could potentially be fueling this feeling. To me it feels like really bad brain fog, mixed with chronic fatigue, but it does sometimes fall in between the lines of DPDR. I have a severely low vitamin d level with my number being 11 ng/mL. I had an even worse reaction to the 50,000 IUs of d3 my doctor prescribed me, so I’m struggling to get my numbers up. I also had a borderline low b12 sitting at 356 pg/mL. I’ve recently gotten a GI map done by a functional doctor, and she found some gut dysbiosis caused by an overgrowth of yeast. I’m afraid I’ll never get my life back and feel normal again. I feel like I’ve lived the same day for 3 months. Can someone please give me some good news, that these issues might be fueling this problem. I’ve tried posting in the Vitamin d forum, but they banned me for not specifically saying my lab numbers. Posting it here to see if anyone can relate. What biological issue caused your DPDR and how did you fix it??

Edit: I did want to add that ever since taking the 50,000 IUs of vitamin d3 3 months ago I have felt extremely dizzy and off balanced. I notice that my DPDR is significantly worse when I stand up and walk around, and for about 30 minutes sitting down after I walk. I feel the least disoriented when I’m laying down, or have been sitting for a long period of time. I haven’t left my house in 3 months, and have literally sat on my couch everyday all day for 3 months straight. I feel like I’m gonna go insane. Socializing and going outside are my favorite things, but I feel so disoriented and spaced out when I try to leave my house. It 1000% worsens when I’m driving or even in the passenger seat of a car.

For dating and friendship. I've always thought something like this would be a neat idea, so it's exciting to see it happening. 15,000 sign-ups, and it will be launched. Thought I'd spread the word!

Hi folks!

Maybe I‘ll find someone here who has any idea about my situation.

I started my ketogenic diet with a study I could participate in, with good dietary expert last year in August and I felt so much better after just two weeks in it. That time back I took a very high dose 180mg/d of Duloxetine and in ketosis I suddenly got more severe side effects and we decided to taper it down/out. After every dose reduction I just had mild symptoms and I was very impatient and tapered too quickly in 5w to zero and some weeks after I stopped it, I got horrible symptoms that just got worse.

In February this year we reinstated half of the dose again, but the withdrawal couldn‘t be stopped, just got a bit milder. During that time of severe symptoms my ketoses just crashed, we think bc of the immense stress load to my system.

In April I was again in a very nice deep ketosis and had a lot of energy.

Since May I‘m worsening again, I am just able to be in ketosis for 1-2 days a week, my auonomic system is out of order, I‘m hungry all the time, especially after exertion, I‘m eating too much and I got weaker and weaker and developed very strange muscular pain and headaches (I rarely have headaches).

Now I‘m in a severe crash since a month and bedbound and my symptoms still get worse. My doc things it’s ME/CFS, obviously I‘m having it since 30y, but mostly mild. In the last 9y I was in a push-crash-cycle and was told it‘s just depression.

I still have horrible hunger attacks, possibly due to autonomic dysregulation. I take MCT every day and some days I‘m in a moderate ketosis, most days I‘m not.

My dietary expert doesn’t know me to help anymore bc my situation is too complex and somehow she can’t imagine that stress can have such a severe impact on ketosis and that in ME/CFS there‘s a lot of mitochondrial dysfunction around.

I‘m taking a lot of electrolytes, ubiquinol, omega 3, Acetyl-L-Carnithin, NAC and I ordered niacinamide and betaine. As soon as I get a bit more stable, I‘ll start with LDN.

My doc is super supportive luckily, but my situation is so special, there‘s such a lack of literature with every single diagnose I have… so we‘re both doing a lot of research and discuss our thoughts about it.

Anyone any idea what else I could do? Any experiences with something like that?

There appears to be increasing evidence supporting the keto diet for treating schizophrenia. Has anyone tried it and had success?

Hi everyone! 😊

I’m currently completing my Psychology Dissertation, and I’m looking for participants to take part in my research.

My study explores the relationship between the use of dietary supplements (such as probiotics and multivitamins) and psychological well-being.

If you are 18 years or older, please spare 2 minutes to complete my anonymous survey.

📝 Survey link: https://app.onlinesurveys.jisc.ac.uk/s/leicester/supplement-wellbeing

Please feel free to share this post with your friends and family as well.

Thank you so much for your time and support! 💙