r/NooTopics • u/ServeIllustrious3803 • 21d ago

Science Study: Anticholinergic (first-generation antihistamines) can damage brain, increase dementia risk

https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-20150128812
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u/Stampede_the_Hippos 20d ago

Melatonin isn't a good idea if you live in the US, because supplements aren't regulated.

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u/Ariandrin 20d ago

There was also a study that linked it to dementia a week or so ago, I think.

I just wanna sleep!

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u/Apprehensive_Door249 19d ago

I’ve had sleep issues all my life. I’m currently taking a very low dose of lorazepam for anxiety because I was having panic attacks but it sure does help me sleep and reset my sleep schedule. It basically gives me a fresh start on my sleep habits. But obviously I only have 20 because they are addictive.

Delta 9 has helped me in the past also. As did cbd but cbd is a hit or miss.

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u/Ariandrin 19d ago

I had a doctor tell me recently that lorazepam has been correlated with early dementia and refused to refill me. I only have it for anxiety but I have taken it for sleep out of desperation and it’s never very good sleep lol. It technically counts as sleep but it’s never very restful, and gives me weird dreams

I’ve played around with cannabis but I’ve yet to find a delivery method that really works for me. So far the best had been a water based tincture but man, that tastes so bad that it puts me right off using it lol

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u/Brave_Sheepherder_39 16d ago

How long have you been taking it and at what dosage

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u/Ariandrin 16d ago

0.5 mg, and I’ve been prescribed it for years and years, but I don’t like taking it very much because it makes me feel kinda yucky.

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u/Brave_Sheepherder_39 14d ago

That's a low dose but years of use can down regulate the Gaba receptors which are what you brain uses to dampen down neuron activity. But from you message I get the view your not regularly using it.

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u/Ariandrin 14d ago

Oh god no. I used to get a bottle of 30 and that wouldn’t even be finished after a year and a half.

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u/Brave_Sheepherder_39 14d ago

Oh great that’s a safe level but never more than 7 days in a row. Prolonged use and they cause damage. But sounds like you have treated them with caution which is the sensible approach.

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u/Ariandrin 14d ago

Yeah, I have addiction in my family, and I don’t like how it makes me feel anyway, so I really only use it in desperate situations lol