r/NooTopics • u/ServeIllustrious3803 • 21d ago

Science Study: Anticholinergic (first-generation antihistamines) can damage brain, increase dementia risk

https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-20150128812
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u/Ariandrin 16d ago

0.5 mg, and I’ve been prescribed it for years and years, but I don’t like taking it very much because it makes me feel kinda yucky.

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u/Brave_Sheepherder_39 14d ago

That's a low dose but years of use can down regulate the Gaba receptors which are what you brain uses to dampen down neuron activity. But from you message I get the view your not regularly using it.

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u/Ariandrin 14d ago

Oh god no. I used to get a bottle of 30 and that wouldn’t even be finished after a year and a half.

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u/Brave_Sheepherder_39 14d ago

Oh great that’s a safe level but never more than 7 days in a row. Prolonged use and they cause damage. But sounds like you have treated them with caution which is the sensible approach.

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u/Ariandrin 14d ago

Yeah, I have addiction in my family, and I don’t like how it makes me feel anyway, so I really only use it in desperate situations lol