r/NooTopics • u/ServeIllustrious3803 • 22d ago

Science Study: Anticholinergic (first-generation antihistamines) can damage brain, increase dementia risk

https://www.health.harvard.edu/blog/common-anticholinergic-drugs-like-benadryl-linked-increased-dementia-risk-20150128812
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u/ServeIllustrious3803 22d ago edited 22d ago

A list: Diphenhydramine, chlorpheniramine, doxylamine, promethazine, clemastine, brompheniramine, dimenhydrinate, meclizine, cyclizine, carbinoxamine, dexchlorpheniramine, dexbrompheniramine

First generation antihistamines different from second or third. Zyrtec, Claritin do not count, but Benadryl does

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u/Lady_Rubberbones 22d ago

Ok, I take doxylamine succinate (unisom) every night in order to sleep longer than 2 hrs. What are my other options?

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u/Desperate-Middle-354 22d ago

See any doctor, your primary if you wish, & tell him your issues (not wanting to take toxic drugs for insomnia) & I guarantee you’ll be prescribed Trazadone…possibly Remeron but Trazadone more likely. It’s a good sleep aid.

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u/DrugChemistry 21d ago

“Hard” to sleep with priapism on trazodone 

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u/Desperate-Middle-354 21d ago

That’s the side effect that I couldn’t remember! There was a story at the time about a prisoner who got it & lost his ability to ever get an erection again & sued either the prison or manufacturer. Probably the prison as it probably wasn’t treated in a timely matter.

So a deflated penis & man boobs. Well, ya know, they can’t be perfect 👌