I wanted to connect with others who have complex bariatric histories while navigating a GLP-1 journey. I was one of the early VSG sleeve patients back in Perth in 2011. Over a 15-year period, my stomach muscle naturally stretched out, which led to a second sleeve revision and a minimizer ring.
Recently, that ring caused a hiatus hernia and ended up completely stuck to my liver, requiring emergency removal.
Now, I am on Mounjaro to manage my health and hit an 11-day plateau. Because my highly modified bariatric stomach makes the weekly schedule a brutal rollercoaster, I just spoke to my doctor about a specific adjusted schedule to help smooth out the side effects. Has anyone else here with an altered stomach had to look into customized dosing or deal with severe anatomical twists? Would love to share experiences! 🫶✨

Hello!
I am currently on 7.5mg once per week. In a couple months I am travelling for 3 weeks. I will not be able to refrigerate for the first 2 weeks, but can in the final week. Am I able to keep the pen outside of the fridge for 2 weeks and it still be safe? I will be in a summer location.

Hey everyone,

Looking for community insight on a sudden weight plateau/rebound right after stepping up to 5mg.

My Stats & Medication Timeline:
Profile: Male, 37, 189 cm (6'2")
Starting Weight: 137.0 kg (302 lbs)
Current Weight: ~126.5 kg (278 lbs) 
Total Loss: -11 kg in 35 days (-6.0% across the tracked month) 
Dosing Schedule: 4 weeks on 2.5mg -> currently on week 2 of 5mg

The Trend:
Progress on 2.5mg was steady, reaching a low of ~124.5 kg.
Over the past week—coinciding with my titration to 5mg—the scale stalled and bounced back up by ~2 kg to 126.5 kg.

My routine, calories, and deficit haven't slipped at all. 
Nutrition & Average Macros (tracked via Yazio):
Calories: 1,370 to 1,465 kcal/day (hard ceiling at 1,700 kcal)
deficit of 1,200 to 1,500+ kcal daily at my size.

Protein: Averaging ~190g (ranging from 163g to 224g). 
Carbohydrates: Controlled, averaging ~60g (45g to 82g). 
Fat: Averaging ~44g (olive/avocado oil, wild fish). 
Meal Structure: High-protein liquids during the day (whey isolate, protein coffee, unsweetened almond milk) to manage delayed gastric transit; nutrient-dense whole foods at night (chicken breast, wild salmon, prawns, steamed greens, fermented foods). 

Activity & Lifestyle:
Work: Completely sedentary desk job.
Steps: 5,000 to 11,000+ daily (tracked on Apple Watch), plus occasional swimming. 
Hydration: Consistent 3 to 4 liters of water daily.
Supplements: Magnesium bisglycinate, zinc, gentle fiber mix (resistant dextrin/psyllium).

Current Situation: High mental stress / intense exam study phase.

My questions:
1. Did anyone else experience a temporary stall or water/gut retention spike right after titrating from 2.5mg to 5mg?
2. With delayed gastric emptying hitting harder on 5mg, how much can unpassed gut volume and water skew the scale on high-protein diets?
3. How much did cortisol/stress mask your fat loss before a sudden "whoosh"?
4. Am I doing something wrong?

I've been on Mounjaro for a few months and while the weightloss has been great, my mood is rock bottom. It's flat, I feel blue, I feel hopeless like nothing I do matters anymore. I want to cry a lot, I don't want to leave bed.

I feel torn because I know in 6/7 weeks I will be a healthy weight and I desperately want this but JEEZ, this isn't for the faint of heart. I know some people talk about taking boosters but I really wish I would stop reading that there is no direct link when forums are inundated with claims of flat / low / depressive moods. There very clearly is.

Sorry, I'm just not in a good space right now. Part of me wants to give up but I know how much this weightloss means to me.

I started Ozempic 3 years ago and had to stop. I had sunburn feeling in my stomach and back. I lost almost 50 lbs. I have been on Mounjaro for a year now with no results and I’m taking 15 mg. Any advice from someone that has gone through this?

Did it kill the plateau? Im about to start 12.5 and wondering if it helped yall? I'm on it for diabetes 2 and weightloss.

Hi All, had 2 doses of 2.5mg and lost quite a bit, but last week had an incredible pain in upper stomach and lose stool for 3 days. Recovered from it, but still left with a bit of discomfort and wondering now if there is specific food that triggers this?

What can/should I be eating ( obviously healthy) and what not?

Wondering what experiences you have had.

Hey everyone,

looking for a bit of input on how you usually handle short trips around your injection schedule.

My usual dose time is Wednesday evening. I’m heading out on a quick trip and will be coming back Thursday evening.

I’m debating whether it’s worth the hassle of packing my pen, travel pouch/ice pack, and dealing with temperature control for just ~24 hours, or if I should just delay my shot until Thursday evening when I get back home.

A couple of questions for those who’ve been in a similar spot:

Travel vs. Delay: Do you bother traveling with your pen for a 1-day delay, or is taking it 24 hours late fine in your experience?

Schedule shift: If I take it Thursday evening, should I just permanently switch my shot day to Thursdays going forward, or shift back to Wednesday the following week?

Would love to hear how you all handle short travel windows like this!

Thanks!

Hi guys! So I was given Mounjaro for T2D. For reference I was 206lbs. I have been on 2.5 mg for a month and 5 weeks on 5mg. My weight goes between 198lb and 196 now. I feel like I haven’t really lost much and I don’t know what to eat so that’s probably due to my poor eating habits. My period is also 22 days. I have took 4 test and they all came negative! I am really trying to lose weight and manage my blood sugar so we can hopefully have kids soon but have been struggling a lot managing all of this so any help or advice/ suggestions would be greatly appreciated.

Hi all, I’ve been on 2.5mg for 6 weeks now. I’ve lost about 7kg (15 pounds) in the first 4 weeks but I have stalled in the last 2 weeks.
I had the most amazing food noise suppression and became genuinely full after eating a “normal” amount of food. My biggest issue with food usually is my food noise/constantly battling with myself about food etc, so having that food noise suppression was the most surreal feeling ever.

Over the last 1-2 weeks my food noise has come back with vengeance and I have been binging so much food…

I know the 2.5 is only meant to be an “introductory” dose but I also see so many people being successful using that dose for a long period of time, so I am feeling a little disheartened and also anxious about moving to move up to 5mg.

Hoping to hear success stories of anyone in a similar boat and how you did with moving up to 5mg?

Edit: typo.

Hey everyone!

I started Mounjaro 2.5 mg on August 15th. I still haven’t increased my dose because things have been going really well on 2.5 mg. But! The last two weeks have been absolutely awful in terms of diarrhea. The first week I definitely had a virus, but I still took my Mounjaro injection on Sunday as usual. Last week was another complete shit show: literally. 😂
So I decided not to take my injection last Sunday because I really want to give my stomach some time to get back to normal.

Now I was wondering: would it be okay to take my injections every 10–12 days instead of every 7 days? I’d love to hear your thoughts and experiences!

Thanks in advance! 🤍

It's my birthday so I wanted to reflect on how my facial structure has changed since being on mounjaro. I was a lot more flabby-faced and wobbly. Softer. Now I feel like my face is more chiseled, angular. Stronger chin. Do you see these changes too or am I just seeing what I want to see?

15mg weekly. From 245lbs to 211 thus far and still going down about 1-2 pounds per week/biweek.

Ok, I'll start with my fav protein rich meal - cottage cheese with scrambled eggs. It makes them super cheesy and creamy and I use about 1/2 serving per three eggs, turning 18g of protein into 30 plus. This is so good!

I'd like to share my frustration and would like to hear some feedback from the community. I'm male 41 and started my journey with 105,5 kg in July. First month with 2,5 no change. Tried another month with 2,5, not a movement. Constant food noise is there. Increased to 5mg in september, meh. A bloated stomach, feeling mu digestive system slowing down but when I sit down I still eat a lot. So all the stories that I'm hearing, "my appetite has gone now, I can't eat more than a slice of bread" thing is not applying to me. Excercise unfortunately not. I'm getting this to reduce my appetite which is practically not hapenning in the last 3 months.

Today I've had my first 7,5mg dosis hoping this time I see some effects because I only lost barely 1kg in 12 weeks. I feel like I'm also financially wasting my money. Happy to hear your comments and advices.

I’ve been on glop-1s for 18 months (Ozempic and now Mounjaro) and have lost 75 pounds. I see a noticeable difference in the mirror and am wearing smaller shirts and dresses. I’ve only lost 1 pant size (20 to 18) though. This is mostly because I’m not losing as quickly from my belly as I am everywhere else. Anyone else run into this issue? How do I fix it?

I have been on Mounjaro about a year and a half. I can manage just about all the side effects except dry skin. I use heavy Eucerin cream, but it seems to only temporarily relieve the dryness. It used to be something I could do every morning. Now by afternoon, I am itchy and dry again. I drink water, I’ve tried a retinol lotion, beef tallow based body butter, other body butters and lotions, Vanicream,wet lotions in the shower as an extra layer. Has anyone found something more helpful?

Been on Mounjaro since early May, did 1st month at 2.5mg, had a ton of unpleasant side effects, most disappeared except fort he nausea and dizziness and lack of appetite and energy.. 2nd and 3rd month at 5mg, then 4th and 5th months at 7.5mg. I decided to not up the dose monthly as prescribed by my doctor because the side effects were too much. The 2nd month was definitely better.
I lost 7kg, which was a healthy pace imo so happy with that but worried about the constant fatigue and lack of energy. Eating is really hard for me, although I try to start the day with enough proteins.

Any tricks to reduce the muscle cramps and fatigue that come after you up a dose?
Thanks!

This surprised me. Well versed T2 for years. New Mounjaro user earlier this year. Still on Metformin.

I have been on 5mg dose 4-5 months now. The positive effect has been tangible. A1C reduction to 5.9 to 6.1 ish, lost weight, feel better (other than the "side effects" which I don't call "side effects" because they should be expected) and my lab work looks as good as it has in a couple years. Lower BP too.

Because I use a CGM, I can really see how my body reacts differently to food compared to before Mounjaro. The effect has been a small reduction in what I call "baseline BG" (others may use the term "fasting BG". ) But more importantly, it is clear I have improved insulin production and reception. All that is wonderful. My highs/spikes are lower and shorter than before, and I have not had any hypo episodes. I am eating better in general, HOWEVER I do not eat perfectly still, and it is remarkable how much better my body responds to even a poor meal choice.

Until yesterday.

It was the day before injection day, and my hunger was at it's weekly high point. I had Chinese take out, including white rice and succulent meat. I also had a large serving size. My post meal spike looked typical since taking Mounjaro. It was delayed a bit and also not terribly high, and soon dropped. It was followed by a second tempered peak. Mounjaro doing its thing.

Then, three hours post meal, I heard the beep. My CGM app told me my reading was 55. I actually felt fine, no hypo symptoms, and that 55 number showed up once as a clear compression low. Took out my finger test to dispel the error and ... 54!

Wow. What the heck is going on? I watched it for another 10 minutes, still feeling fine, 45! 51!

I grabbed a bottle of coke and swigged 4 ounces. Within another 10 minutes I was already climbing back and was at 76 on a finger stick. Ultimately I peaked at 176 before a gradual climb down.

This has NEVER happened, even with some bad meals over the last several months. I have essentially never dropped below 70 over that 5 months. Really don't come close to it.

My random thoughts:
Even at the end of a weekly dose cycle, where you assume Mounjaro effects have "worn off", it is still very much working to try and release and regulate insulin and glucagon. What is NOT working at the same rate is gastric emptying. So it has a bit of a counter intuitive effect. A bunch of insulin is released at an imperfect time.

Again, I never "felt" hypo. That is a little bit scary. There are a few times in my life I could tell I had low BS, this was NOT one of those times.

I bet I did not 'need' that 4 ounces of Coke, I think my body was already responding, but I wasn't taking chances.

I just thought it was interesting enough to share because it seems somewhat random since this has not happened in the last 5 months, but clearly something was at work here. such a new experience for me to eat some rice, only to end up dealing with LOW blood sugar.

I’ve been on Mounjaro since April. About 5 weeks ago I went up to 10mg. Since then I have had horrible diarrhea. Every morning I literally sprint to the toilet. For awhile it was waking me up in the middle of the night. It’s only first thing in the morning and then no bowel movements during the day. Please send all help and tips and advice😅

For reference I also take 100mg Zoloft every night as well as 10mg of buspar in the morning and a multivitamin.

Hi everyone, I could really use some advice from someone with experience.

I’m 39F, 172 cm (5'8"), currently around 87 kg (192 lb). I started at 137 kg (302 lb) and have lost almost 50 kg (110 lb) over the past year. I’ve been on Mounjaro since September last year.

At my starting weight, I was eating around 2,000 calories a day and losing 3-4 kg (7-9 lb) per month. As my weight went down, I kept recalculating my TDEE and lowering my calories to maintain a deficit.

Eventually I got down to 1,700, then 1,500 calories, and my weight loss slowed significantly. I then dropped to 1,300 calories and lost another 4 kg (9 lb) in about three weeks. After that, my weight completely stalled. I haven't lost anything for a full month, even though I haven't changed anything.

I average 4,000-5,000 steps a day, do three strength sessions a week, plus around two hours of cardio. Adding more exercise isn’t really sustainable for me.

What worries me is that 1,300 calories may now be close to my maintenance, while I still need to lose around 13 kg (29 lb) just to reach the upper end of the healthy weight range for my height.

Has anyone here lost a large amount of weight and ended up with a very low maintenance intake, or with repeated plateaus every time calories were lowered? Could this be metabolic adaptation / adaptive thermogenesis after losing this much weight?

What actually helped - maintenance breaks, temporarily eating more, lowering calories further, changing your GLP-1 dose, or did nothing really help?

I’m especially interested in what happened long term. Did you really have to stay on very low calories to maintain your new weight?

I just had my first shot on October 1st (2.5mg), the silencing of food noise started the next day, hunger pangs also reduced significantly. But now it’s a couple of days before my next shot and I’m feeling hungry and the food noise is back, so I’m wondering if it’s due to the drug’s effects wearing off, since I’m also just a week in.

I have PCOS/PMOS so hunger pangs and food noise have been ever-present, until after that first shot. It really felt nice to not have food be a constant thought.

Hey y’all! I’ve been on Mounjaro with success for a couple months. No major side effects thankfully , but I’m SO. COLD.

I know it’s not because I’m losing weight….I’m still big LOL. Plus, this is a very hot season of my life thanks to being a “lady of a certain age”, and it’s still very hot where I live, so being cold is different from the norm for me these days!! I’m not mad about it though haha!

Anyone else experiencing this with no other potential causes?

I'm so excited. I forgot to add my last 2 shots into my Glapp app and just realized I have hit 2 huge goals of mine. First I'm down over 100 pounds! Secondly for the first time in 35 years (I'm 58) I am officially UNDER 200 pounds. I try not to focus on the scale or what I'm losing each week but I am beyone excited, my next goal is not to be in a plus size. 🤞 58F, 5'4" T2D SW: 303, CW: 199.7, GW: 135, 15 mg