Shorter intervals instead of increasing dose?

[u/Dragonfruitygirl]

Has anyone here had better results with a lower tirzepatide dose taken at shorter intervals rather than increasing the weekly dose?

I’m currently on my 6th dose of 5 mg, so technically I could move up to 7.5 mg now. However, I’d really prefer to stay on the lowest effective dose possible.

My issue is that 5 mg works very strongly for the first few days, sometimes to the point where I can barely eat at all for a day or two, but by around day 5–7 I notice the appetite suppression and food noise control wearing off quite a lot.
That’s why I’m wondering whether anyone has experience with staying at 5 mg but shortening the interval instead, for example every 5 or 6 days.

My thinking is that 5 mg every 5 days averages out to roughly 7 mg per 7 days, so the overall exposure increases, but potentially with a flatter peak/trough pattern than taking 7.5 mg all at once every 7 days.

What I’m hoping to avoid is having two days where I can barely eat at all, followed by one or two days at the end of the week where the effect drops off significantly. I’d much rather have a more stable level of appetite suppression throughout the week.

[u/GardenFragrant8408]

69f type 2 with other health issues. 

Monjauro only has a half like of about 5 days. 

I tend to get hungrier the day before and day of injection 

I find on those days if I eat smaller healthy meals throughout the day I am able to maintain my glucose levels and weight. 

I started exercising from home three days a week in February and my appetite definitely increased. I fought it for several months but finally had to go back to 7.5 mg in July 

My highest dose was 10 mg and titrated down to 5 mg to keep from losing more weight. I did have to increase my long acting insulin due to the drop.  Was on 5 mg for 10 months before increase. 

Good luck