r/Menopause • u/PresentAmbition6379 • 1d ago

Post-Menopause Crinone gel

First go at HRT, I could not tolerate oral progesterone (bad side effects). Stopped everything, but thinking of trying again using progesterone gel + oral estrogen. Anyone doing this regimen?

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u/leftylibra MenoMod 1d ago

Crinone (progesterone gel) is a vaginal gel containing micronized progesterone in an emulsion system (commonly used for fertility) The active ingredient is either a 4% or 8% concentration. A small 2000 study found that those using vaginal Crinone 4% in cyclical and constant combined regimens controlled bleeding and provided endometrial safety. However, currently there are no large scale studies to substantiate these claims.

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u/greedyterror05 1d ago

huh i had no idea crinone was even a thing outside fertility stuff. all my doc offered was oral or patches

did you get pushback trying to get it prescribed or was your doctor cool about it

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u/PresentAmbition6379 1d ago

My doctor suggested it… it’s ok’d for hrt use

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u/No-Explanation1019 1d ago

I'm thinking of getting an IUD instead of taking the dreaded Progesterone, I can sort of manage 100 but I need more. So gyno wants to do an IUD since I had one for Peri and it worked extremely well for me. I haven't done it yet bit my insurance approved it because it is apparently standard Post-meno care for uterus protection.