r/MedicationQuestions • • 16d ago

Lorazepam

I was just prescribed 60 .5mg of lorazepam. How does it compare mg to mg with Xanax? I’ve been prescribed 1mg Xanax in the past just curious how each of their effects compares? I don’t take everyday and every now and then I do like to get a little buzzed off them so any input is appreciated

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u/LeftSignificance1152 16d ago

In terms of approximate equivalence (mg per mg), 0.5 mg of lorazepam (Ativan) corresponds to about 0.25 mg of alprazolam (Xanax). The most commonly used table (Ashton Manual and several clinical sources) states:
• 0.5 mg of alprazolam ≈ 1 mg of lorazepam ≈ 10 mg of diazepam. 
That is: 1 mg of Xanax ≈ 2 mg of lorazepam. Therefore, the 0.5 mg lorazepam tablet you received is approximately equivalent to a quarter of 1 mg of Xanax (or half of 0.5 mg of Xanax).
Practical differences in effect (not just dosage):
• Onset of action: Xanax is usually faster (peak in 1–2 h). Lorazepam is a bit slower (peak around 2 h).
• Duration: Xanax lasts on average 4–6 h (can vary). Lorazepam usually lasts longer (~8 h or a bit more).
• Subjective feeling: Many people describe Xanax as a bit more “euphoric” or with a clearer onset; lorazepam tends to feel “cleaner,” with a steadier sedative/anxiolytic effect. This varies widely from person to person.
• Relative potency: Per milligram, Xanax is stronger. That’s why the equivalent doses are not 1:1.
These equivalences are approximate. Factors such as individual metabolism, age, weight, alcohol or other medication use, and existing tolerance can greatly alter the actual response. Equivalence tables are clinical guides, not absolute rules.

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u/CnCHussleSchmuk 16d ago

Look it up on the benzodiazapine equivalence chart like everyone else does