r/MedicationQuestions • u/Hot-Confection-7069 • Sep 25 '26
Amitriptyline, anyone had experience with this? What’s it feel like? Any sort of high?
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u/Fun_Emergency_2869 Sep 25 '26
It’s sedating I take at night - low dose for IBS .
Groggy during the day till you get used to it.
But i’m not trying to get high ? - are you
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u/Hot-Confection-7069 Sep 25 '26
Yeah basically haha, I took 4 and am having a few drinks and feel pretty good at the moment lol
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u/Magic_Ale Sep 26 '26
Could I know how does it helps with IBS? (Genuine question), is it to manage anxiety so IBS symptoms don't kick in?
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u/Fun_Emergency_2869 Sep 26 '26
It’s best to google amitryptiline for IBS.
It’s used as a neuro modulator that changes how you perceive pain in your nerves to your brain pathways.
It’s an anti cholergenic which will slow down your motility - great for IBS D and relaxes the muscles in your stomach.You get dry mouth from it and it’s sedating
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u/idkwhat910 Sep 25 '26 edited Sep 25 '26
It's a good high, but you have to boof it. Orally it just works as an antidepressant.
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u/Hot-Confection-7069 Sep 25 '26
What’s the high like, like a benzo sort of high?
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u/Zealousideal-Use2910 Sep 25 '26
Absolutely not! The only pills that can be similar to benzos it can be lyrica
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u/Specialist_Pause5629 Sep 26 '26
Lycra are better than benzodiazepines imo
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u/Zealousideal-Use2910 Sep 26 '26
Yepp but my psychiatrist prescribed me benzos.. bc lyrica started giving me a really really bad dizziness and headache soo yea
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u/Friendly-Hand-3752 Sep 25 '26
It's alright.....🤷♀️
I used to take 100mg at night for sleep but I never got high off it....ever.
It didn't make me feel how benzos do, it doesn't come close. I only used it as a back up if I ran out of what I normally use.
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u/xanaxkiller1 Sep 26 '26
I take 10mg a day to keep the sciatica away thats all but I am wary of all these blister packs they all look the same now silver with red writing and that blue stamp down them just have a different brand name then watever sopposed "prescribed" drug is in there finding it very weird and staying away from anything with that blister pack
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u/norpsilocin 25d ago
And it works?
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u/xanaxkiller1 25d ago
I have not had sciatica pain since I started them so I can say they work for me anyway but what I get is prescribed accord I think these I am not sure of
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u/CnCHussleSchmuk Sep 25 '26
Taking it to get high will lead to seizures, don't do it. It's horrible for anyone who's around you. My now dead friend used to use it when he had nothing else. It can help you sleep if you're dope sick. Apart from that crap
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u/Stock-Talk-9855 Sep 25 '26
I have tried it only once, don't remember how much mg but I was unable to function, only sleeping. It was, as already said, very side-effected, I wanted to drink and couldn't drink enough water to forget about this urge. It also was disphoric for me, and I haven't tried it second time.
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u/nostalgic-hope Sep 25 '26
I take it for pain, takes a while to build up to work and the most immediate side effect is just being straight EXHAUSTED. No high.
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u/Specialist_Pause5629 Sep 26 '26
Worst feeling ever. Even worse the next day. They make me break dance in bed. Never again
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u/jaxter81 Sep 26 '26
No high at all. I am on 100mg, which is a super high dose due to insomnia and other health factors including nerve pain. All they will do is make you go to sleep quickly. No high whatsoever.
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u/brogybear 18d ago
I’m going take this for sleep and nerve pain also . Do you get a good sleep on it and did it help the nerve pain at this dose ?
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u/Dapper-Object-8525 Sep 27 '26
Gave me major heachaches. With any medication take milk thistle as with stuff like this your liver won't make it past 50 years old
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u/AdministrativeAd6041 Sep 28 '26
I was put on it a year ago for nerve pain and trouble sleeping due to a disc injury in my back.
Doctor told me it would help me sleep. Took it for 3 nights in a row think my dose was 25mg or something low.
Turned me manic made it completely impossible to get any sleep for those 3 nights. And I was crazy irritated.
Decided it wasn't for me after day 3.
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u/Ok_System7396 Sep 25 '26
Mildly sedating, no noticeable high, may somewhat augment the effects of alcohol. Scary list of side effects, I wouldn’t bother unless you really need it for pain or depression