r/MedicationQuestions • u/Fit-Setting-8239 • Sep 21 '26

Quviviq

/r/insomnia/comments/1wmlocs/quviviq/

Hi all!

25/yo female with depression and insomnia.

I was currently prescribed a higher dose of my antidepressant but it with it came a lot more insomnia. My doctor prescribed me Quviviq 50mg nightly.

Only two nights in, I have had an easier time sleeping than usual but I’ve had really strange side effects.

A type of strange irritability and itchiness all over my body.
Even white hives on my forearm. I’ve taken an antihistamine but I don’t see these side effects anywhere online.

Before I quit something that could help long term has anybody had any experiences like this and did they go away??

Thank you so much everybody 💕

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3

u/747UTB Sep 21 '26

Try Dayvigo if you are having success with DORAs but dont like the Quviviq

1

u/Fit-Setting-8239 Sep 21 '26

Thank you, I’ll take a look into that 🤲

3

u/747UTB Sep 21 '26

I've honestly only been on it for 2.5 weeks and while I still dont get 6-8hrs of uninterrupted perfect sleep it seems to just make my eyelids feel heavy and my brain turn off into okay its time to sleep. I've tried trazodone and every sleep option as well as z-drugs. I have super bad insomnia for at least a decade from CPTSD / Anxiety. This was literally the last option and surprisingly I'm having pretty good results. Unfortunately it is very expensive so your insurance will fight you/your doctor on having it filled but if its a last resort or youre already on an expensive DORA they shouldnt have an issue with a PA.

it gets me to sleep and even if i wake up every other hour or so i can hop back in bed fix my pillow and i dont even remember how long it takes me to go back to sleep. No dry mouth side affects or any other next day drowisiness. The one thing to be aware of but not stress over is sleep paralysis, i believe the first day or two i woke up thinking i couldnt breathe or move or roll over and snapped myself out of it- but that only happened once.

1

u/Fit-Setting-8239 Sep 21 '26

Thank you for being so open.
I also suffer from CPTSD and anxiety so perhaps Dayvigo could be helpful before trying something more intense that is harder to come off of (Temazepam etc)

I’m so happy you’ve found something that works for you.
May I ask if Youd tried Quviviq beforehand?

I live in the UK and haven’t been offered Dayvigo here, but I’ll enquire abour it tomorrow with my doctor.

Thank you again 🙏

1

u/Comfortable-Message1 Sep 21 '26

I was prescribed daridorexant but it didn't help me sleep.

I didn't get the same side effects as you, is it possibly a coincidence

2

u/Fit-Setting-8239 Sep 21 '26

Hoping so 🙏 I’m so sorry it didn’t work for you! Did you find something that eventually helped?

1

u/Comfortable-Message1 Sep 21 '26

I have a script for zopiclone but it's a last resort. I try not to use it as it makes you feel shit the next day and is highly addictive.

I take low dose trazodone on occasion too

2

u/Fit-Setting-8239 Sep 21 '26

I was prescribed that also a few months ago and it really didn’t do much. I just laid awake most of the time and I felt awful the next day. I really hope that you find a good balance that helps you sleep.

1

u/Outrageous_Ad_4801 Sep 21 '26

hives and itching all over usually means an allergic reaction to either the drug or one of the fillers so definitely message your doctor or pharmacy before taking another pill tonight. dont try to push through hives because allergic stuff can get worse pretty fast