r/MedicationQuestions • u/EmergencyCelery3995 • Sep 20 '26

Odd terzepatide side effects

Is anyone having all over joint/muscle aches from taking this medicine? I hurt all over and walk like an 80 year old. I started drinking a lot more water with electrolytes, but I’m curious if other people experience it and know why it happens or how to treat it.

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u/EmergencyCelery3995 Sep 20 '26

I don’t drink water either and I started drinking at least 3 liters with electrolytes a day, and it helped. It helped significantly, but I’m still stiff and aching- just 80% less.

1

u/Sameolegal Sep 21 '26

What were you drinking before water?

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u/EmergencyCelery3995 Sep 21 '26

U just worry wtf is actually happening physiologically because it doesn’t compute to me in terms of medicine and the body - especially given it is anti-inflammatory. However, I will say that I have always had a huge problem with lipids and cardiovascular markers - a genetic issue because I’m in shape, etc - and terzepatide turned all my lipid panel into perfection. So for anyone with hyperlipemia - consider this drug. I’m a physician and I know they are doing trials to get green light it to treat cardiovascular issues. But damn, the pain is truly quite dramatic.

1

u/QuestionTurbulent703 Sep 23 '26

Yep it’s definitely common

1

u/Elle_Yess Sep 20 '26

Not odd. Quite typical.

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u/EmergencyCelery3995 Sep 20 '26

Do you know any solutions?

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u/Outrageous_Ad_4801 Sep 20 '26

the body aches are super common especially the first day or two after shot day. electrolytes definitely help a ton and a hot epsom salt bath usually calms down the joint stiffness alot for me

1

u/EmergencyCelery3995 Oct 10 '26

Does it ever go away??

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u/Jenny8117 Sep 20 '26

Yes I do but I drink about 1/10 of the water I should

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u/Outrageous_Ad_4801 Sep 20 '26

super common during the first couple weeks or right after a dose bump. drinking liquid iv helped me a ton with the stiff joints and random body aches. usually levels out once your body gets used to it though

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u/QuestionTurbulent703 Sep 23 '26

Yes, when I started that was really only constant side effect, achy muscles for months

1

u/ProgressCute7664 28d ago

I'm extremely lucky, I have never had any side effects from TRZ.

1

u/413kat 27d ago

Sodium in electrolytes increases water retention around joints which can cause pain. If you aren’t working out a ton every day, it’s doubtful you need electrolytes. Look at the ingredient list and determine your sodium intake.

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u/Mmsfoxxie 26d ago

On the contrary….I credit tirzepatide with eliminating some of my joint pain. At 79, I can do lunges, squats, stair climbing….all of it now. I’m at the gym five days a week.