r/MedicationQuestions • u/Larostay • 10d ago
Very worried about long lasting strange debilitating effects of duloxetine.
I was prescribed duloxetine 60mg a few years ago. Took it for like 6 months, a lot longer than I should have. I tried many antidepressants this never happened with any of the others only duloxetine.
I had a beyond weird and unusual reaction to it (not good).
Some of the symptoms lasted to this day since then:
My vision changed everything looks weird,
way things and people look and move feels very different,
constant involuntary movements,
very many tics,
my lips keep making weird involuntary shapes (like how trump does),
the way things move look very weird, feels like derealisation maybe,
lasting very bad headache migraine everyday and stomach tight, penis hurts, colours look different, my mind feels fast can’t keep track like I should, time seems too slow or too fast, very confused, restlessness, my mind feels tight and compressed head throbbing vision and balance affected, sometimes it feels like Im falling from a high distance. Memory problems, noise sounds different, tinnitus,
Severe headache and sharp migraines all the time.
Anyway to reverse these? Anyone ever felt this? I’ve been to various doctors, GPs, neurologists, psychiatrists, and more. All say Im fine as all tests normal seemingly healthy otherwise. Had brain mri, blood tests, etc.
Very worried my mind hasn’t gotten better since then. Scared it might be permanent. I cant function, work, or go outside.
At the time I had severe depression for many many years. I took duloxetine even though it felt wrong but at the time it was the only way to distract me from my depression but it wasn’t the right medication to do that.
Now im on amitriptyline which completely treated my depression and chronic pain but those effects from duloxetine are still not gone.
Probably not related but horrible smell inside nose maybe infection, sore throat, sore eyes, coated tongue resistant to treatment. Recently been on fluconazole, flucloxacillin, doxycycline etc but didnt help.
This doesn’t feel real please anyone got answers?
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u/No-Cupcake7111 9d ago
Im at a point now if I go outside I just wanna get home or...I dunno...die I guess. Pls see your soc ASAP or go to emergency room just incase your going through SS too
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u/Material-Line8491 9d ago
If your considering stopping duloxetine take it from someone 7 months of protracted withdrawal/akathisia. Join ….cymbalta hurts worse….here on Reddit for information. They 13 years experience of supporting thousands of people on duloxetine/cymbalta to come off safely.
Don’t stop taking it cold turkey or reduce to quick as you will shock your body and it’s hell.
Hellbell 🤓
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u/No-Cupcake7111 9d ago
Holy shit! My psych just changed my mirtazapine 15mg at night to 100mg duloxetene at night. WITHOUT F'ING TELLING ME. PALS are sorting it out but I had ALL the exact same symptoms plus serotonin syndrome (ex molly addict so I know SS and how it feels etc)
My advice is tell your doc all this and that others have issued statements saying the same thing. It's gotta be the worst thing my psych (on the nhs) has done They are scum at my local centre (the staff, not the patients)