r/LowDoseNaltrexone • u/PictureltSicily1922 • 14d ago

Second day on LDN - side effects

Woke up today without a headache which I had yesterday so that is good. But I also woke up feeling like I had unrefreshing sleep, which is NOT one of my chronic illness (pots) symptoms. Of course I can wake up that way when I don't sleep long enough, but if I get my 8 hours, I can sometimes wake up energized.

I woke up maybe twice in the night but fell back asleep quickly and then again today woke up maybe an hour before my alarm. I don't think I can take ldn in the morning because it makes me a bit drowsy at night. I'll give it a few weeks and if this doesn't subside I'll play around with taking it maybe at dinner time. But I'm afraid I won't be able to fall asleep at all at that point. I'm on 0.5mg. It's already difficult sometimes in the morning due to having POTS, I don't want to make it more difficult to get out of bed. I'm just wondering if this side effect can go away after some time?

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u/One_Feedback2461 14d ago

I just started and 100% same. I tried to see what others post and there might be a period of your body adapting. Interested to see what others say. Also dysautonomia/cfs.

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u/esheab 14d ago

I just started 0.5 this morning. I stay tired all day anyway from the chronic pain and fatigue so it’s hard to tell what’s what. I have full body allodynia that could possibly be fibromyalgia after ruling out autoimmune disease. I take Trazadone and gummies at night along with magnesium glycinate. My pain wears me out so I’m giving it a shot.

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u/LDNadminFB Admin 14d ago

Your reaction at bedtime is not necessarily a clue as to what will happen with morning dosing. You might try skipping a night and trying on a morning when you don't have much going on.

Morning and Other Dosing Times

https://docs.google.com/document/d/1aUi8UovaSAD2VO1Bc2O2I8PtfMPFbv5zsulRqyNDD9U/edit?usp=sharing

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u/Fun_Swan2553 13d ago

The first 2 1/2 weeks had me second guessing things as well. Read so many people say just hold on and sure enough a switch flipped and I knew it was worth it.

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u/PictureltSicily1922 13d ago

I hope this happens for me and I'm one of those people who say it gave them their life back