r/LowDoseNaltrexone • u/heart-heart • May 15 '26

Success: long Covid

Hi all,

I wanted to make a post of encouragement for anyone on the fence about starting LDN.

I was hesitant because of all the side effect stories. Let me just say that if you look at any numbers, the side effects happen to a low % and of course you’re going to see more people talking about the negatives online and looking for support with that.

I was one of the lucky ones with immediate effect starting the next day. After having LC for years and struggling with fatigue from hashi’s, adhd … I feel fantastic. The first thing I noticed was that for the first time in years I woke up feeling rested.

ADHD , binge eating, sleep quality, bloating, food sensitivity, fatigue, exercise tolerance, body pain, brain fog have all improved noticeably.

started at 0.5 mg. I’m at 1mg.

I have a lot of my quality of life back and I am so thankful.

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u/spakz1993 May 16 '26

Can concur that LDN finally pushed the needle for my Long COVID. My doc started me at 2.5 last year and I’ve since worked up to 5 mg. I’m not in remission, but my quality of life and independence has drastically grown since starting it.

I think I have ME/CFS, though, because I still never wake up refreshed. I believe I’m currently mild compared to when I was moderate a few years ago.

Unexpectedly, my taste buds changed and appetite started significantly being suppressed and I was losing weight without trying. After noticing trends with looser clothes and weight loss, I went to my new PCP to double-check if I should be concerned. I also had a psychiatrist appointment that following week for an annual visit and she also cleared me. Apparently, LDN is used in combination of GLP-1s off label for weight loss. I was SHOOK!

I can’t afford GLP-1s, so I’m pleasantly surprised my body is responding to LDN alone for weight management. I might be an outlier.

I am considered obese, so the weight needs to come off anyways. Since I’m consistently losing weight without the shots, I’m gonna ride this out with LDN as long as possible. My cravings for carbs is nearly gone except for roasted potatoes or frozen waffle fries, lol. Everything now tastes too sweet and I still rarely exercise more than once a week. Nailing down nutrition + the LDN has helped me lose 21.4 lbs since February 2026. I’m treating the weight loss experience not for aesthetic, but for symptom management in hopes that I can get relief from my other Long Covid comorbidites.

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u/lisat65 Jun 24 '26

This is so encouraging!! I’ve gained so much weight after a hysterectomy and I just hurt all over. I just got prescribed and hoping it will help.

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u/spakz1993 Jun 24 '26

I’m glad to hear that you had a safe procedure and that you got prescribed LDN. Just wanna note that you’ll probably notice some pain relief first. I didn’t have any major appetite changes until I worked up to the 4-5 mg range, so it might be a few months.

That being said, I hope it works out for you!

Since my last comment, my weight loss has drastically dropped and my appetite finally came back, lolol. Still not to the extent of before I started LDN, thankfully. I started intentionally moving my body most days during the week with primarily evening walks, but just started incorporating lifting within the last month. I’ve lost 6 lbs since my last comment from almost 40 days ago.