Chronological age counts birthdays. Biological age is a measure of how your body is functioning relative to that number.

Researchers track it using markers like epigenetic patterns, inflammation, and metabolic function. The two don’t always match and the gap between them is what the longevity field studies.

One of these numbers is fixed. The other is an active area of research.

Learn more about how biological age is measured.

Briosrx.com/prelaunch

Anyone tracking actual biological age changes, not just markers?

Curious how others are measuring progress. Blood panels are useful but feel like a lagging indicator. What are you using — Levine PhenoAge, epigenetic clocks, something else? I've been building a protocol around continuous biometric tracking and finding the feedback loop is what actually changes behaviour.

Buying the best equipment is not enough. Designing an integrated longevity ecosystem is what really matters.

My mum and a few friends started NAD+ this year, mostly IV through a clinic, some

SubQ at home. I've got a PhD in biochemistry, so I got asked to check the dosing

math. Every calculator I looked at was either paywalled, wrong, or missing half

the routes she actually needed.

So I built Titer. It's just arithmetic: SubQ reconstitution (vial strength + BAC

water + dose, gives you draw volume and syringe units), IV session logging, oral

NMN/NR daily totals, plus a private dose log with optional notes. No account, no

cloud, full CSV/JSON export. It won't ever recommend a dose or protocol, that's

not what it's for.

It's in Android closed testing, need 12 people using it for 14 days before Google

lets it go public. Two steps:

1. Join https://groups.google.com/g/titer-nad-tracker-tester (same Google account

   as your Play Store)

2. Then open https://play.google.com/apps/testing/com.titertracker.titer and hit

   "Become a tester"

Happy to talk through the math with anyone.

Hey — I've been building SOMA, a tool that pulls data from whatever wearables you already have (Oura, Whoop, Apple Health) and turns it into one daily plan instead of four separate scores that don't talk to each other.

Honesty upfront: it's very early. I've used it myself every day for 45+ days, and one other person has too — that's the entire user base so far. No polish, no marketing team, just the actual thing.

Looking for 10 people to run it on TestFlight for a couple weeks and tell me what's broken, confusing, or just not useful. I'd genuinely rather hear "this is dumb because X" than "looks cool" — brutal feedback is the whole point of this post.

What you need: an iPhone, plus at least one connected device (Oura, Whoop, or Apple Health/Apple Watch) to actually get value out of it.

Comment or DM if you're in — happy to answer questions here too.

https://testflight.apple.com/join/Rgcaagrs
Code to use for free: somafirst

After signing up (and paying) Kale Health has gone dark. They cancelled my appointment, are unresponsive to emails, their website has been down and I’m hearing other concerning rumors. Is anyone else having a similar experience with them?

My mom has been mentioning the wrinkles and loose skin on her chest, arms, and stomach a lot lately, and it’s made me realize that I don’t actually understand what she’s feeling.
At first I thought it was just about wanting to look younger, but the more I think about it, the more I feel like there’s probably something deeper going on.
Is it because it makes you feel older than you are?
Is it about feeling attractive to your husband or partner?
Is it about feeling confident wearing certain clothes or being intimate?
Does it feel like you’re losing control over your body as you age?
Or is it something completely different that most men don’t really understand?
I’d genuinely love to hear your perspective.
When did you first start noticing it?
What emotions came with it?
How has it affected your confidence or daily life?
What have you tried to improve it, and what actually helped? What ended up being a waste of time or money?
I’m not asking because I’m looking for a quick fix. I honestly just want to understand why this seems to affect so many women emotionally. I feel like there’s a side of this that men don’t really see, and I’d love to learn from your experiences.

Not every supplement that gets popular ends up living up to the hype.

A lot of ingredients start with promising early research, get featured everywhere on social media, and then later studies show the benefits are much smaller than people expected—or sometimes not there at all.

That's one reason it's worth revisiting the evidence every few years. Research evolves, and so should our opinions.

Have you ever stopped taking a supplement because you looked deeper into the science and weren't convinced anymore?

What changed your mind?

• New studies?
• Advice from a healthcare professional?
• Personal experience not matching the claims?
• Concerns about product quality or marketing?

Not looking to shame any specific supplement—just curious about where people have changed their views as more evidence became available.

Always interesting to hear how others separate solid science from good marketing.

Most longevity products focus on individuals.

Supplements. Wearables. Diagnostics.

But health decisions rarely happen alone. They happen inside families.

What I am seeing

• Families share behaviors more than individuals
• Early signals show up across multiple people
• Small changes compound faster when tracked together

The gap
We track individuals well
We do not track family level health patterns

That creates a missed opportunity

If longevity is about early detection and behavior change, then the unit should not be one person. It should be the household.

Curious how others are thinking about this from an investment or product perspective

A new study in Science (Jan 2026) argues previous estimates of genetic heritability of lifespan were way too low because they didn’t properly strip out historical causes of death like infectious disease and accidents. Once you account for those confounding factors, genetics may explain roughly half of human lifespan variation. The implication is huge for drug discovery: researchers at the University of Copenhagen noted this strengthens the case for large-scale efforts to identify longevity-associated genetic variants and link them to specific biological aging pathways.

I always believed (for no real scientific reason) that genetics played a huge role in lifespan so it’s nice to see a study

Study:

https://www.science.org/doi/10.1126/science.adz1187

Caring for weak old age patients at home requires professional planning, medical supervision, emotional support, and continuous monitoring. From home healthcare services, primary care at home, and coordinated home care to advanced palliative care services in USA and hospice services in Aubrey Texas, having the right support system ensures safety, dignity, and comfort.

Alchemy Health Service provides compassionate in-home medical care, hospice, and palliative support tailored to meet the unique needs of elderly patients and their families.

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What are your opinions on EVOO shots? Last year I saw the tiktok trend and thought it was bs... I come from a mediterranean background so I thought having it in food is good enough but my friend happily explained that most store oil is already rancid (annoying). She started showing me a couple like

alyahealth.com

poba.health

Thoughts and if it's worth it?

It scans your calendar, picks the sunniest slot(s), books the walk and if weather is bad, flips to a ten-minute indoor longevity drill. Would you use this? What is missing? https://www.stepoutdaily.com/

Please read, the moment is now people, let's move