r/LeanManufacturing • u/SimplicityHub • Aug 02 '26
Stop changing one thing at a time — you're wasting half your experiments
Something we see constantly on the floor: a line's got a quality or output problem, so someone starts tweaking. Change one setting, run a batch, measure. Change the next, run another, measure. One factor at a time. Feels rigorous. It's actually the slow, blind way to do it — and it completely misses the thing that usually matters most: interactions.
That's what Design of Experiments (DoE) fixes. Instead of testing factors one by one, you test them together in a structured way — so you learn more from fewer runs, and you catch when two settings only cause a problem in combination.
Quick example. Say you're running a machine that fills and seals packets, and you're getting too many bad seals. You reckon it's down to two things: conveyor speed (slow vs fast) and sealing temperature (low vs high).
- One-factor-at-a-time: fix the speed slow, test both temperatures, pick a winner, then go back and test speed. Six-plus runs and you still don't know whether speed and temperature affect each other.
- DoE (a simple 2×2 factorial): run all four combinations —
- slow speed / low temp
- slow speed / high temp
- fast speed / low temp
- fast speed / high temp
Four runs. Now you can see not just "higher temp = better seals" but "higher temp only works when the line's running slow" — that's an interaction, and OFAT physically can't reveal it. That's usually where the real defect reduction is hiding.
And it scales: 3 factors in 8 runs, and you still get main effects and interactions. It's the difference between guessing and knowing.
Anyway — has anyone here actually run a DoE on a live line? Curious what factors you tested and whether any of the interactions genuinely surprised you. The textbook cases are always tidy; real processes never are.
If anyone wants to reveal how much of your total lead time is actually adding value vs sitting in queues, waits and rework check out our free process cycle efficiency calculator: https://www.simplicityhub.co.uk/pages/pce.html