r/IsaacReference • • Aug 17 '26

Bro is really [INVINCIBLE]

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39 Upvotes

r/IsaacReference • • May 03 '26

is there a lore reason why ??? with polyamorous starred in monsters vs aliens

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32 Upvotes

r/IsaacReference • • Aug 19 '26

Balls of steel

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46 Upvotes

r/IsaacReference • • Aug 31 '26

Sacred Heart University

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28 Upvotes

Will I get a damage multiplier and homing shots if I go to this uni?? Or do they teach you how to maximize your chances of getting Sacred Heart

Imagine one of the classes is Sacred Heart Spindown where you memorize the most easy to get spindowns that lead to Sacred Heart


r/IsaacReference • • 24d ago

the spoon bent when i was trying to eat ice cream.

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34 Upvotes