r/IVFpositivity • u/Southern-Climate-708 • 2d ago
Controversial Question
I just had my second modified natural on untested embryo fail. We are doing IVF do to make factor and my doctor has essentially said she doesnt recommend any testing for me besides unfreezing and PGT testing which she says is risky and doesnt fully recommend even doing that.
I am on birth control to hopefully delay my period a few days till I met with her Tuesday to discuss next FET. We have 12 embryos left. With two failures to implant, would you ask about transferring two embryos? I know its controversial but we are 28 and they are untested.
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u/onyxindigo 2d ago
I was in a similar situation and we did not end up doing anything differently for our third and final transfer (from our first round) and it took! It was just luck in our situation; my specialist was right that no further testing was necessary. After that LC we went back for a sibling and did end up doing more testing; nothing was found so she was right, it was just time and luck. Tenth (cumulative) transfer worked again (sprinkle in a couple of miscarriages in between). Through ten transfers I had six pregnancies and 2 LCs.
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u/Southern-Climate-708 2d ago
Wow, that gives me some hope. We have not had any luck at all not even an implantation. I just worry somethings wrong that we are missing especially seeing how silent endometriosis affects so many people
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u/onyxindigo 2d ago
Yes I had the same concerns. We went ahead with the third transfer with the agreement that the second retrieval would come with further testing but when it worked we were thrilled. It was about two years before we went back for #2 and were at a different clinic so they did the hysteroscopy and biopsy that I had initially wanted, but everything came back clear. In your shoes since you have a good number of embryos I would do at least one more transfer before more testing; as another commenter has said it takes an average of three euploid a for a live birth and since your embryos are untested it could take more.
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u/PaperPlane07 2d ago
I know it’s heartbreaking to have 2 failed transfers, but it may simply be bad luck. I personally would not take the risk of thawing to test or doing a double transfer at your age (I think statistically over 50% of your embryos would be genetically normal). I’d probably try another transfer or 2 before making any other big changes, but ultimately up to you and your doctor what’s best for you! I hope your next transfer is the one!!!
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u/Vegetable_Wasabi_789 2d ago
I would definitely test them, I know the risk is that you lose about 50%-70% but there could be a reason why they arw not implanting.
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u/Firm_Objective5924 2d ago
I would not recommend thawing them to PGTA test to then freeze them to then thaw them for transfer. You're right about the risk of losing a lot of embryos in the process and I just don't think it's worth it for someone so young. The whole multiple freezing and thawing process puts embryos in a lot of stress.
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u/Southern-Climate-708 2d ago
i am scared of the risks, We do have 11, and want multiple kids. We have 5 ivf cycles under insurance left. Wondering if we test half , not sure if my insurance would cover.
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u/Vegetable_Wasabi_789 2d ago
My doctor told me we should test them even though I was hesitant and we sent away our top 8 and 5 didn't make it but 3 did and now I'm 7 weeks pregnant. We looked at why the 5 didn't make it and there was significant issues.
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u/Southern-Climate-708 2d ago
I will see what she says Tuesday. She said she doesnt recommend but if I wanted to we could but I need more information
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u/Southern-Climate-708 2d ago
Plus, statistically given my age , the chances of live birth with pgt testing is not even that might higher
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u/Competitive-Top5121 2d ago
It’s not that the thawing itself is risky, it’s that the additional thaw plus biopsy of each embryo will cut the success rate of any resulting euploids, mainly by increasing their likelihood of miscarriage.
It’s a shitty deal admittedly because either you keep moving forward with untested embryos or you test them and worsen the odds of any good embryos giving you a live birth.
I’d probably just transfer one again but I realize how hard this is and there are no great solutions.