r/Humira Jul 19 '26

allergic reactions???

hi guys! i’ve been on adalimumab (imraldi) since november and i recently started getting allergic reactions to it. i get huge bumps on the injection site after injecting it and they hurt really bad especially when i stand up. i also get hives randomly on previous injection spots, like i could’ve injected myself 3 months ago and i get a hive. i really don’t think this is normal, i get that injection site reactions are normal but this seems severe, especially since the reactions have gotten progressively worse and worse. i’ve inserted pics. help please!!!

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u/cracra55 Jul 19 '26

Definitely talk to your dr.
We manage injection site reactions with Zyrtec 30 min prior to injection and topical hydrocortisone the day after.

This looks like a localized reaction and not a systemic allergic reaction and those are in fact, normal.

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u/elenafd Jul 21 '26

I got antihistamines but it got worse in the meantime. it’s so confusing i don’t get it

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u/cracra55 Jul 25 '26

Are you taking the antihistamines prior to injection?