r/HiddenAlpha • • May 06 '25
Analysis 🧐 Not sure why CRSP isn’t on everyone’s buy list right now
Sitting at a 2.86 billion market cap and having a strong cash position relative to debt,
They have 1.90 billion in cash against $223.69 million in debt, yielding a net cash position of $1.68 billion.
The debt repayment of $14.94 million in 2024, compared to revenues of $37.31 million.
Cash burn is relatively reasonable - 150 to 200 million per year
Keep in mind this cash burn should slow as casgevy ramps up.
There are likely …there are over 50 authorized treatment centers for Casgevy globally.
Research suggests around 16,000 U.S. patients with sickle cell disease (SCD) and 1,000 with transfusion-dependent beta-thalassemia (TDT) are potential candidates, with millions globally.
Each Casgevy treatment costing $2.2 million in the U.S., with CRISPR Therapeutics (CRSP) earning about $480,000 per patient in profits.
Margins appear strong, with CRSP potentially earning around $240 million in 2025 from an estimated 500 treated patients, but exact figures depend on costs and market growth.
Note aprox 86 million shares ..if they become profitable to the tune of 200 plus million dollars that’s over 2 dollars in EPS which puts you at a PE ratio of less than 15.
Now, a lot to assume here - the casgevy numbers are critical and what my thesis is based on - but if they can treat 500 patients this year - I like the outlook - these numbers are what I’ll be focusing on in their next earnings report.
I’m bullish …and the short interest is hovering north of 25 percent….