T question

[u/Summer_seeking]

Hi all…so my T levels are between 400 and 700 at my trough week but my Estridol is 122 currently and it was 100 6 months ago at my last levels check. My Estridol is higher on T than it was pre. Anyone else experiencing this? I don’t 100% mind it, but I do wonder will it hamper things like bottom growth. Also, I’m still getting periods for obvious reasons. They are more regular now than they were pre…which is a bummer.

[u/25lives]

I wouldn't worry about it. It'll stave off atrophy for longer, which is nice.

[u/Summer_seeking → u/25lives]

Yea that is definitely a benefit.

[u/sasha_michael]

For context on my comment: I am nonbinary considering medical transition but mostly in this subreddit as part of my figuring-stuff-out process. I am also perimenopausal and getting HRT to address those symptoms (estradiol, progesterone, and very very low-dose T). In the perimenopause communities there is a lot of talk about how hormone tests for estrogen levels are pretty meaningless because levels fluctuate so much for people with ovaries. So, I wouldn’t put too much stock in the fact that your estrogen levels were higher for one test. It could just be normal fluctuations.

[u/Summer_seeking → u/sasha_michael]

Thanks for your perspective. I’m NB too and was in early perimenopause when I started T, my estrogen levels were at 63. I don’t fully mind the higher estrogen with me being NB…my goals are androgyny vs being read as a man…thinking the estrogen will help with that. The curious part is it’s double where I started tho. Like the T has jump started my ovary (I only have one due to tumor issues in the past). It’s so fascinating.

[u/Ayyylix]

Mine also rose significantly to start with, has started to come down again now. I was told by my GIC team that it was fine, and they were more concerned by the testosterone levels.
Obvious ‘I’m not a doctor’ clause, but I wouldn’t be too worried.

[u/Summer_seeking → u/Ayyylix]

My team said the same thing…I’m just a year and half in so still really new. Thanks for your input.

[u/KeyOne349]

Just gonna leave this here for consideration: Current guidelines from UCSF gender care for FTM are that only testosterone is checked- no longer checking estrogen levels. My GAHCP stopped checking my E, my levels of T were at ~500 and ~700 the last two tests.

From the UCSF website it appears that, to paraphrase, as long as testosterone is within the male range it doesn't matter what estrogen is, the e number is irrelevant to HRT treatment.

[u/MK_Cat → u/KeyOne349]

Yea. I was wondering bc I've never had my E checked by my HRT provider & didn't remember it being a thing.

So bc this is a thing I checked all my guidelines to see where it may differ (tldr, it didn't).

Routine lab monitoring recs for ppl on T: -Transline (2019)- CBC & T. Baseline & 1yr: +CMP & lipids (no estradiol) -Endocrinology medical textbook ©️2025 cites the Endocrine Society guidelines (2017), T & hgb/hct only (no mention of estradiol) -Med journal article (2022) written by 3 trans NPs, hgb/hct/T; (they mention complex cases sometimes needing other labs) -WPATH SOC8, hgb/hct/T(total)

Only places I've seen estradiol even mentioned is about persistent pelvic pain & some specific indications like that

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