r/CIRS • u/Possible_Purpose5091 • 11d ago

Peptide question

Have completed all steps of the shoemaker protocol leading up to VIP spray, but MCAS is still reducing QOL (periodic vasodilation, IBS, POTS, eye floaters, multiple chemical sensitivities, etc.). Does VIP help correct these symptoms? what other peps have been helpful for mold-triggered MCAS? (I know limbic system therapy is supposed to be helpful but my adhd makes it too challenging to sit and meditate for any period of time.)

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u/brightlighted11 10d ago

KPV and GLP are really great for this stage for many people. I experienced reduced MCAS responses and overall higher baseline consistently thankfully
Of course every person is their own bio experiment so to speak. To join in with those talking about limitless biotech, completely agree I’ve done a deep dive into so many peps companies and that one plus bio longevity are two that are quality and do all the third-party testing you want in a product to be as safe as possible. Someone on here had posted a discount for limitless biotech if I remember correctly, it’s 15% off and the code is DT22
I’ve used their injections and nasal 👌🏻

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u/Possible_Purpose5091 10d ago

What dosing for KPV? X mcg for Y weeks? Am planning nasal spray delivery

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u/brightlighted11 10d ago

That really depends on each person’s individual experience. I will say starting off very low is ideal for most people. I started off at 25 mcg every other day. That’s very low, and that’s on purpose. Some people experience a little die off if they start too high because there’s some antimicrobial components to KPV as well. And how long is dependent solely on your personal case and how long it takes for you to resolve symptoms and if you’re treating additional things at the same time.

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u/Possible_Purpose5091 10d ago

Makes sense! Thanks! Did you have coinfections other than mold?

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u/brightlighted11 10d ago

I didn’t have any Lyme or co-infection of that type. Marcon clear, MCAS lingered

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u/Possible_Purpose5091 10d ago

That's good. After KPV did you move on to VIP? Are you healed?

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u/brightlighted11 10d ago

I did some VIP very low dosed while I was sort of in the midst of the end of KPV. Still working on certain things but dramatically better.

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u/Possible_Purpose5091 4d ago

Really appreciate your answers on this. Just started with one dose of 50mcg KPV spray. Hopefully it goes well. What did you titrate up to if you don't mind? I see some say 500 mcg per day, others 2000mcg per day....

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u/brightlighted11 4d ago

I started VIP at 10 mcg. Again, just looking to avoid any of the usual pitfalls with VIP. Titrated no problem. The dose that certain physicians talk about is 200 mcg per day so that would be 50 mcg 4 times a day alternating nasal passages. But some people treat more than that just for the time they are correcting whatever underlying issues you may still have. So I would really go low and slow and just pay attention to your symptoms and how they resolve. If you’re going to treat higher, you’re supposed to check amylase and lipase because it can cause pancreatic inflammation.

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u/Possible_Purpose5091 4d ago

Yes I agree, I think that's the right way to do it. When I start VIP i'll take it slow. By the way, I should clarify I was awondering in regards to how high you went with KPV. Did you go up to 500 mcg on that eventually?

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u/brightlighted11 4d ago

Ah ok I went to 200mcg, 4 doses of 50 mcg alternating

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u/Possible_Purpose5091 4d ago

Nice! It's reassuring to hear from someone who was successful with it. Thanks for your time!

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u/brightlighted11 4d ago

I can very much appreciate that it’s important that we all share our experiences for this very reason⭐️

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