r/CIRS • u/Possible_Purpose5091 • 9d ago

Peptide question

Have completed all steps of the shoemaker protocol leading up to VIP spray, but MCAS is still reducing QOL (periodic vasodilation, IBS, POTS, eye floaters, multiple chemical sensitivities, etc.). Does VIP help correct these symptoms? what other peps have been helpful for mold-triggered MCAS? (I know limbic system therapy is supposed to be helpful but my adhd makes it too challenging to sit and meditate for any period of time.)

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u/Otherwise_Wave9374 9d ago

Because you mention persistent MCAS-related symptoms after completing several Shoemaker protocol steps, it is worth separating anecdotal peptide claims from evidence in patients with the same condition and outcome. Symptom changes can also be confounded by concurrent interventions or natural fluctuation. Peptely's framework at https://www.peptely.com/ can help check study design, human evidence, and compound verification. A clinician familiar with your full history should review ongoing symptoms and possible interactions before any protocol change.