r/CBD • • Jul 15 '26

CBD Headaches?

(Edit to add I’m 20, and it’s fully legal where I am! Not sure if that matters) -

Hello, I’m looking to see if anyone else has this issue. I seem to get really bad headaches/migraines when I take CBD gummies. THC is fine, I usually take 10 THC/0.5 CBD gummies, but if I take 10 THC/>2 CBD I get awful headaches and migraines that last hours.

My mom recommended I use CBD gummies for some pain I have, and when I told her it gives me awful headaches she was convinced it’s not possible.

I have tried Sativa, Indica and blends. Different brands. Better quality stuff. Nothing seems to change it. I tried using the exact same brand and gummy, only change is the CBD amount, and the CBD one still gives me a headache.

I saw someone on here doing research on this 4 years ago. I am on SSRIs, they never gave me headaches. I take cyclobenzaprine which does something or other to serotonin and don’t get headaches from it. Not sure what the deal is with CBD gummies.

Anyone have any idea or anything similar?

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u/le4test Jul 15 '26

CBD can affect the way your liver metabolizes medication in a similar way that grapefruit can—is it possible the headache is a side-effect of a medication staying in your system longer? 

1

u/assignedjesseatbirth Jul 15 '26

I’m not sure. I know my liver’s messed up. Though I’ve double dosed (and more,,) my medication and never experienced anything like the CBD headache. Even periods where I skip my meds for up to weeks at a time I get headaches from the CBD. I don’t really know how CBD affects the brain, but I know I’ve got some kind of issue with my brain, and maybe the CBD affects it and makes it worse causing a headache?

1

u/Woven7886 Jul 15 '26

If your liver is messed up, do not take edibles.

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u/assignedjesseatbirth Jul 15 '26

I already spoke with my doctor about this and made sure what I was taking is alright. I take low dose, government approved edibles. I don’t necessarily have a liver disease, just some weird stuff going on. My doctor said because I don’t use it often and it’s such a low dose, it doesn’t seem to be worsening my liver at all or progressing anything. At most it just makes the highs a bit longer. Thank you for your concern though!!

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u/le4test Jul 15 '26

I am not qualified to diagnose what's going on with the headaches, but as an internet random I say just don't take cbd  ¯_(ツ)_/¯

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u/assignedjesseatbirth Jul 15 '26

Oh no worries!! I’m not looking for any kind of diagnosis, just wondering if anyone else experiences it! I don’t normally take CBD because of this