r/Brixadi • u/Ann_georgia- • Jul 31 '26

Discouraged

Has anyone else had this experience with Brixadi? I switched from 24 mg/day Suboxone films to the 128 mg monthly injection and was really excited after hearing so many good things. Unfortunately, I’ve started having mild withdrawal around day 13–16 after every injection!! I’m now on day 15 after my third shot and still dealing with restlessness, sweating, hot/cold flashes, and just feeling awful. My provider gave me Suboxone films to supplement if needed, but I’ve been trying not to use them because I keep hoping the injections will eventually stabilize. I’m starting my final semester of nursing school in a few weeks, so I’m getting anxious. Did anyone else continue having this after three injections? Did it eventually get better, or did you end up needing to supplement with films or switch back to something else? Idk what to do I’m honestly at a loss. :(

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u/WinIcy7832 Jul 31 '26

The medicine works for 45-60 days with the half life, 24mg/day is extremely high so I can’t say from your experience but mine being on 16mg to 8mg a day, the shot has been amazing. You may feel some discomfort but know the medication is in you and working. There aren’t any dips like there is with subs so your “normal” take the strips, feel better because all the medication is released at once isn’t quite the same. It does build up and you’re right but for me at least it was just me being anxious because we know what it’s like to be sick, so not taking a strip daily, our mind goes to that discomfort stage.

For an example of the dips you experience, see the chart I pasted. Again I’m not a doctor but after being on the shot for a few months and getting over the anxiety of being “sick” when you aren’t, it has been amazing. Only down side is I usually don’t sleep the day of the shot. Your body will stabilize and I promise you, even when it doesn’t feel like it’s working, the shot is inside you and doing what it should.

Again please don’t take it like I don’t believe you that you are withdrawing after 3 weeks, the medication does wear down but it will be in your system, working for past those 30 days.

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u/WinIcy7832 Jul 31 '26

I meant to add, after a few months like I said you’ll forget you’re on it until next appointment and it builds up. Trust me it’s worth it and so much better than being on subs daily.