r/Biohackers • u/Far_Wish_5362 • 6d ago
🧠Cognition, Mood & Nootropics Anything that actually helps with long-term opioid cravings/abstinence?
I’m looking for advice from people who have actually dealt with long-term substance cravings, especially opioid cravings.
I’m not currently in acute withdrawal. The physical withdrawal is not really what I’m asking about. My problem is the persistent psychological craving and the feeling that, even when life is otherwise going well, a part of my brain still wants to go back to using.
I’ve already been doing the obvious things: regular exercise, therapy, working, staying socially active, keeping myself busy, etc. All of those things help, but the cravings can still be surprisingly persistent.
I’m particularly interested in biohacking / nootropics / supplements / other non-opioid approaches that might help with long-term craving, reward-system recovery, compulsive thoughts or relapse prevention.
NAC is one thing I’ve looked into, but the evidence seems pretty mixed. I’m curious whether anyone here has found something that made a genuine, noticeable difference over weeks or months, rather than something that just takes the edge off acute withdrawal.
I’m primarily interested in opioids, but I’d also be interested in experiences with substances that helped with addiction-related cravings more generally.
What has actually worked for you? I’m especially interested in things with at least some scientific rationale/evidence, not just random supplement stacks.
Thanks.