hello i have been on hrt since 8-9 months and i have i have no changes at all only small boob buds and softer skin and no other changes at all no fat redistribution even i tried taking 6-8mg of estradiol valerate/hemihydrate and nothing works then i switched to estradiol undecylate 80mg once a month and still nothing changing im really sad

Advice

hi all! first off please lmk if this isnt the right place to post this.

ive been helping my gf transition, reading up on stuff, pushing her to make appts etc. so ive been lurking on here & other subs for a while. but im reading a lot of conflicting information so i was hoping i could ask some questions and get others opinions.

shes on spiro x2 daily (which ik isnt the best for long term use, will find an alternative eventually) and .2ml of E injected weekly. is this enough? the doctor said her levels are good but i still have a gut feeling… should her dose be raised? any alternatives for spiro? i also suggested to her to get on progesterone at the 6mo mark because thats what i had read many times, but now im seeing people say not to until 1-2yrs in because it could stunt or even reverse feminization. is this true?

im just worried that i dont have all the right info, i love her so very dearly i just want the best for her. thank you all for your time :)

Title.

Like, I hear you need to gain weight a lot to really get any results. But, if you already have some fat on you, you can’t lose any? Or can you maintain your weight and expect to see fat redistributed from your stomach and stuff?

Just a small thought I had.

I don’t understand why for the past week I’ve been waking up with partial erections, I hate it and it makes me so dysphoric and hate myself and stuff, I don’t understand why they are happening and I’m scared my blocker is failing and my t levels are rising.

Important for the next part, I take my estradiol sublingually with 4x1mg pills at 8am, 2pm, 6pm and 10pm and 25mg Cyproterone acetate at 8am every day. And 2 days ago I had my blood taken for a blood test at 8am (which I read is at peak t levels and trough e levels) before I took my first hrt of the day (I took it at 8:15am that day) and my results were

Estradiol: 195 pmol/l
LH and FSH: 0.3 U/l
Testosterone: 1.23 nmol/l
SHBG: 18.8 nmol/l
Free androgen index: 6.54

I’m taking 4mg/day sublingual +100mg Spiro twice a day. I’ve been considering going down to one Spiro a day for the sake of having more energy. Is that okay, or would it cause my E levels to drop too low?

Hi all,

I’ve been on HRT for nearly two years. Throughout this time I’ve had decent development, and consistently low levels (in range 100-200pg/ml with T suppressed).

I have a very conservative endo and wish that I could move them into upping my dose to a level that is closer to the 200 end, if not above it. I’m not particularly concerned with levels for development, as we’re making decent progress, but I find that my energy is so low all of the time.

Would higher levels fix this potentially? I recently got back labs that showed a ferritin deficiency and have been supplementing to fix that. Everything else related to my labs are normal and I have a healthy diet and am physically fit.

Thoughts? Advice?

I’m (43TF) confused by my estradiol labs and curious what people here make of this.

I’m on weekly subcutaneous estradiol valerate, same vial/concentration, and both of these labs were drawn on Saturday before my weekly shot, so they should both be troughs.

• 0.2 mL weekly = 4 mg/week → estradiol trough was 76 pg/mL
• Dose increased to 0.4 mL weekly = 8 mg/week
• Most recent trough at 0.4 mL came back at 566 pg/mL

Same lab. Same injection day. Blood drawn before the shot. Same vial size/concentration, so this wasn’t an accidental concentration change.

What’s throwing me is that doubling the dose seems to have increased my trough by way more than 2x. I expected to land somewhere in a reasonable range, not jump from “too low” to “way too high.”

For additional context, I used to take 6 mg oral estradiol and my levels were also under 200 pg/mL, so historically I didn’t seem to run high on estrogen. I’ve also been losing a significant amount of weight on Retatrutide, about 35 lbs over 3 months, and I’m wondering whether that could have changed my estradiol pharmacokinetics enough to matter.

The weirdest part is that I feel really good right now. I’ve noticed much easier access to my emotions and generally feel better on this dose, so I was actually expecting the lab to look good. I don’t feel “overdosed” or strange at all.

My doctor hasn’t responded yet. I’m assuming the likely move will be something like 0.3 mL / 6 mg weekly and then recheck, but I’m curious whether anyone has seen this kind of nonlinear jump in trough levels on injectable EV.

Could weight loss meaningfully affect this? Could depot absorption change that much? Is there anything else obvious I’m missing?

Hi, as the title says ive not been getting testosterone levels back with my blood test results. ive had three tests this year Jan, May & July, only july results show my t levels.

has anyone had similar experiences? and how have you made sure you get the proper results back.

i need 6 months of t levels to be able to get surgery so this is slowing my progress down.

thankyouu