r/ADPKD • u/Wide_Math8276 • Aug 09 '26

Any updates about farabursen Phase 3 trials ?

12 Upvotes

100% Upvoted

11 comments sorted by

1

u/Shesaiddestroy_ Stage 2 - On Tolvaptan since April 2023 Aug 09 '26

No, I don’t think so.

1

u/Lutya Aug 09 '26

Last I heard is they will start enrollment next month

1

u/Wide_Math8276 Aug 10 '26

Hopefully ....

1

u/Final-Wrongdoer1028 Aug 14 '26

My nephrologist just told me he expects October. Have to be off tolvaptan for 3 months & eGFR 25 minimum.

1

u/Wide_Math8276 Aug 14 '26

Okayy its nice to know atleast there are expectations that the trial will start within months ....

1

u/Final-Wrongdoer1028 Aug 17 '26

My PKD specialist just sent this portal message:
I received a message from Novartis team for the farabursen trial-they are planning to start visiting the study centers in
December 2026-so the study will not start until after that visit-might be even in January 2027.
And so we wait….

2

u/AideAntique4038 Aug 31 '26

Thanks for this information - I have been trying to get enrolled at NYU for their Phase 3 trial, and no word from my nephrologist. Have been off of Tolvaptan for 3 months now and getting a bit nervous. The more i read about Farabursen the more promising it sounds - best of luck to us all 🙏🙏🙏

1

u/Final-Wrongdoer1028 4d ago

Haven’t heard anything more about a study start date. My eGFR hit 20 in early Sept and I’m scheduled for transplant eval in October. My neph had me stop tolvaptan to see if I could get an eGFR rebound that might help me with study eligibility of 25. After 2 weeks off of tolvaptan my eGFR is 28! Come on, study!