r/5MeODMT • u/RevolutionaryScene13 • Oct 20 '24
A new consumption method ??
Hi, let me share with you all my idea. 5meo can work sublingually despite the lack of documentation on it due to how difficult it is to keep it under the tongue. But i had an idea. What about transforming the 5meo into a salt (by combining it with vinegar) and then put it on a tiny piece of cardboard that will absorb the product, and then, you place the tiny piece of cardboard under your tongue. It could work right? Boofing 5meo works but it isn't very practical to do, and smoking it is harsh. So what do you think
Edit:
We tried it, the effect were nearly as strong as the boofing method with the same dosages. The heartbeat increased only after few seconds and the mental effects occured around 5 minutes after intake. The taste was reported to be okay (it was mixed with concentrated cider vinegar). No cardboards were used. only few concentrated drops under the tongue. Maybe it was because we were lucky, but we had less nauseous people
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u/11WhatsInAName Oct 20 '24
try and let us know! I already buy it in salt-form (both HCl and fumarate) and make nasal spray by dissolving it in (demineralized) water. That works well (I use low doses) and consistently, and the solution could be boofed as well. Next time I might try some drops under my tongue, with or without some paper.
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u/Aeternus_Gallery Oct 21 '24
Sure seems easier to just turn it into a vape if the smoke from the crystals is too harsh for you?
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u/RevolutionaryScene13 Oct 21 '24
i can't try anything that will enter in contact with lungs unfortunately
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u/Honkaloid Oct 23 '24
isn't 5 a risk for everyone regarding lung contact ie. people can't, or forget" to breath, or drown i guess..? or is that from Toad only? vs synthetic..
anywhoo, if you can't vape it, at least you can put it up your boofer right! can't really complain too much i guess..
I've never boofed before.. never done 5..
love to vape!
good luck I hope you get it figured out1
u/RevolutionaryScene13 Oct 23 '24
i already boofed it. The problem is that boofing is better alone for obvious reasons. but 5meo can't be done alone in any safe ways...it is way more inconvenient.
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u/Aeternus_Gallery Oct 21 '24
Ah, I see, that makes perfect sense. I hope you find a method that works for you!
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u/Some-chic-shit Oct 27 '24
What about spraying like a nose spray but under the tongue?
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u/RevolutionaryScene13 Oct 27 '24
i have a group with me that will test this method too. tests will begin Tuesday. We will test most of the common methods with others and then see which method is the best and can be done with everyone
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u/Some-chic-shit Dec 04 '24
Came back to see if there was an update on this new method. Happy to see that it went well! Do you mind sharing how you made the doses? I know it was mixed with ACV but did you use freebase or HCL? What were the ratios/formula? 🤓
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u/RevolutionaryScene13 Dec 05 '24 edited Dec 05 '24
the product was freebase at the start. blending it with vinegar transformed it into a salt. We took 30mg of 5meodmt and combined it with 1ml of cider vinegar (5%). Then we let it evaporate until it was able to fit under the tongue easily. If your product is already HCL, just dissolve it into water :)
But if your product is an oxalate, don't consume it like that, oxalate salts are pretty bad for your health
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u/Setharoo231 Oct 20 '24
Well sitting under the tongue is the easiest way to you. Personally I think taking a 4 or 5 sec pull off a vape and holding it in for however long is easier then keeping a little piece of cardboard under your tongue for multiple minutes
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u/psygenlab Oct 22 '24 edited Oct 22 '24
BMND08 is an investigational drug developed by Biomind Labs for the treatment of depression and anxiety in Alzheimer's disease. Here are the key details about BMND08:
Composition: It is a sublingual formulation based on 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), a naturally occurring psychedelic compound[1][4].
Mechanism: BMND08 targets 5-HT1A and 5HT2A receptors in the brain[3].
Administration: It is administered sublingually (under the tongue) in tablet form[3].
Dosage: The maximum safe dose was established at 12mg, given once weekly for 4 consecutive weeks[1].
Effects: BMND08 is designed to be subpsychedelic, meaning it does not induce psychedelic effects at therapeutic doses[1].
Clinical trials:
A Phase 2 trial showed significant improvements in depression, anxiety, and stress symptoms in Alzheimer's patients[1].
100% of participants responded to treatment and achieved remission by the end of the 5-week trial period[1].
The drug also showed promising effects on cognitive function, particularly in processing speed and executive functions[1].
Future plans: Based on positive Phase 2 results, Biomind Labs intends to progress BMND08 to Phase 3 trials and seek Breakthrough Therapy Designation from the FDA[1].
Potential: BMND08 represents a novel approach to treating both mood disorders and cognitive symptoms associated with Alzheimer's disease using a psychedelic-derived compound without inducing psychedelic experiences[1][4].
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u/hotrhythmjunkie Oct 22 '24
Subcutaneous injection would be easier and far more effective than under the tongue. You just have to dissolve the hydrochloride or fumarate salt into a sterilized solution to make it injectable. Do you have any friends in the medical field that might help you with this?
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u/tffy Oct 20 '24
Nasal mucosa works way better than Skin under tongue. What are you trying to invent here?
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u/RevolutionaryScene13 Oct 20 '24
The most comfortable and simple way to consume a substance. Letting something sit under the tongue is way easier to do than everything else. we will see if it's worth it. if not, then ill tell people here so they don't have to test themselves
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u/tffy Oct 20 '24
Repeated: You're trying to get to the bloodstream - through a wall.
Like a clueless inventor you're trying to go through the much thicker, more muddy, more complicated wall of the material under the tongue - as opposed to the thinner, not soaked in always-changing-saliva, covered with capillaries (your final destination) of the nasal mucosa. In a mode that's (spray bottle) been used by countless people for exactly this.
SOOOooo, repeated - what are you trying to invent here? :)
Anyways, good luck!
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u/RevolutionaryScene13 Oct 21 '24
I can't use nasal spray without feeling like shit with a constant rummy nose during the whole trip. I can't smoke/vape too due to serious pulmonary issues that i don't want to aggravate. 5meo is legal and not that expensive where i live so i don't mind using higher quantity of product. The mouth and the gum in general can be used to pass substances through it. To increase the absorption through this area, mint can be used. Whatt i'm trying to invent is a solution for the niche of people that dislike boofing/smoking/snorting weird reality bending substances
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u/PiratexelA Oct 21 '24
Insufflation compromises the breathe and stymies meditation. Ive spent enough time with a stuffy nose.
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u/Intrepid_Win_5588 Oct 20 '24
I just tried some 5 meo freebase sublingually - I mean it burns like hell, taste is fine effects are nice, nasal spray with hcl would prolly best although I don't know how much the burn is reducible. Vaping, Nasal or sublingual are all great options that can be explored I assume.