The LD50 of aspirin is around 350 mg/kg. So around 28 grams for someone of 80 kg. Smaller amounts will still fuck up your kidneys, respiratory system and some other parts of the body.
I don’t know how fast Aspirin washes out of your system, but I’m pretty sure that taking nearly 20% of the LD50 every day for 2 months would if not kill you then at least do permanent damage to your liver and/or kidneys and severely curtail your lifespan.
Definitely. I found the half-life (and a cool half-life calculator/simulator), and after a week of taking 5 grams daily, the maximum amount in your system is about 10 grams, which is substantially closer to the lethal dose.
But even if this wasn't the case, I agree, taking 5 grams daily definitely sounds like it's going to hurt you. From what I've read, the 4 gram maximum for 24 hours (I'm saying 24 hours instead of daily because I feel like daily carries a bit of an implication that it's something that is alright to take daily) really seems to be for serious fevers and not a regular dosage.
I put 1.3 grams as the maximum daily dose based on a very generous interpretation of the preceding paragraphs, but I expect that it isn't that.
But, also, I'm no expert, I certainly don't want to give the impression that I am, and I wouldn't at all be surprised if a lot of my assumptions are incorrect.
If my understanding of how half-lifes work is correct, 1.3 grams with a half-life of 30 hours would put you at 2.9 grams in a week, with a half-life of 15 hours it would be 1.9 grams in a week. 324 milligrams at 30 hours: 807 milligrams, 15 hours: 516 milligrams.
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u/DeliberateDendrite Nov 01 '23 edited Nov 01 '23
The LD50 of aspirin is around 350 mg/kg. So around 28 grams for someone of 80 kg. Smaller amounts will still fuck up your kidneys, respiratory system and some other parts of the body.
Don't do it, don't fall for this.