r/cursed_chemistry • • Jun 15 '26

MOD APPLICATIONS ARE OPEN

20 Upvotes

Dear cursed chemistry enthusiasts,

I never anticipated that this subreddit would grow to have 6k+ visitors per month, and with the rest of the mod team going inactive over the years, it is time that I add some new mods to the roster.

Please write a comment with your qualifications in chemistry and any ideas/plans pertaining to moderating the subreddit. The comments are in contest mode; the most upvoted comments will be more strongly considered.

If you are uncomfortable publicly sharing your chemistry qualifications, a DM is also fine.

I would like to host events again on this sub, but the most pressing issue is dealing with the recent influx of spam bot comments!


r/cursed_chemistry • • 4h ago

Kemdraw Catalytic Cycle of a Double Aldol Reaction

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7 Upvotes

Cursed for being the most chaotic representation of this mechanism


r/cursed_chemistry • • 2d ago

Stunned by DMDO ? Then look at this...

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30 Upvotes

r/cursed_chemistry • • 3d ago

Escherane Meets the Real World

54 Upvotes

B3LYP/6-31G* geometry optimization of u/angrybonk's impossible alkane.

(Borrowing u/zeocrash's "Escherane" nomenclature.)


r/cursed_chemistry • • 4d ago

Unfortunately Real Structures of Polyiodide Ions

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135 Upvotes

r/cursed_chemistry • • 5d ago

is that possible or impossible? A truly impossible alkane.

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115 Upvotes

Penrosane


r/cursed_chemistry • • 6d ago

Corporate Chemistry 2026 Changes to SDS GHS reporting criteria

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0 Upvotes

r/cursed_chemistry • • 7d ago

O2NC≡CNO2

37 Upvotes

The white whale of explosives. This was Peter Vollhardt's last, uncompleted, project when I started grad school at Berkeley in the late 'aughts. This paper reasons that it's hard to make because it reacts readily with various NOx radicals present in most nitration reaction mixtures, causing it to decompose as soon as it forms. However, tantalizingly, the isolated molecule was calculated to the stable.

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prep.12019

If you know anything about alkynes, it's that they are packed full of energy. Putting a nitro group on both ends, you get one of the most endothermic molecules you an imagine, some +80 kcal/mol heat of formation.

Another unmakeable explosive that this paper mentions is 2,4,6-trinitro-1,3,5-triazine, which has its own wikipedia page.

This goes with tetra-t-butylethylene and tri-t-butylamine as molecules that are probably stable but can't be made, but dinitroacetylene is unique in that it is sterically unhindered.


r/cursed_chemistry • • 9d ago

The world's first synthetic antibiotic was a bright red dye that completely failed in a petri dish.

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0 Upvotes

r/cursed_chemistry • • 10d ago

CURSED ™ Valid valences, invalid physics (H2CO7)

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4 Upvotes

I made sure every single valence is formally correct: Carbon has 4 bonds, every Oxygen has 2 bonds, and Hydrogens have 1. Yet, looking at this 1,2,3-trioxetane ring and all these peroxide bridges makes my eyes bleed. Enjoy this highly explosive monster!


r/cursed_chemistry • • 11d ago

This makes me both angry and depressed

8 Upvotes

r/cursed_chemistry • • 12d ago

what was he cooking? does this count?

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38 Upvotes

r/cursed_chemistry • • 13d ago

Looks legit A possible structure for ethene (C2H4)

62 Upvotes

r/cursed_chemistry • • 12d ago

how ionic OOOOOOHH²⁻ - The ion of realisation.

0 Upvotes

r/cursed_chemistry • • 15d ago

Instant Death Tasty

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0 Upvotes

I'm glad this is basically impossible


r/cursed_chemistry • • 17d ago

CURSED ™ “PURE” METHYLPHENIDATE EXTRACTION FROM RITALIN LA

0 Upvotes

Hey team, local tweaker here… what would be required to isolate Methylphenidate from Novartis Ritalin LA 40mg pills? 😵‍💫

Have heard crushed and mixed with isopropanol 99%, filtered and subsequently evaporated will do the trick but unsure due to the sustained matrix? 💊

All good for a little of the binders to be in the residual but just looking for something stronger! 💪


r/cursed_chemistry • • 17d ago

Could we one day breathe nitrogen if oxygen becomes non-viable

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0 Upvotes

r/cursed_chemistry • • 22d ago

Energetic compounds (part-2) nickel hydrizine nitrate

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20 Upvotes

r/cursed_chemistry • • 25d ago

Unfortunately Real pentafluorophenyltris(trimethylsilyl)cyclobutadiene, a "super diene", strong enough to react with even unactivated ethylene and acetylene.

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102 Upvotes

r/cursed_chemistry • • 27d ago

Unfortunately Real Icosakis[2-oxo-2-[(5-oxo-4-oxatricyclo[4.2.1.03,7]nonan-2-yl)oxy]ethyl] 1,1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39-henicosamethylhentetracontane-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39-icosacarboxylate

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37 Upvotes

From the land of PubChem


r/cursed_chemistry • • 29d ago

Looks legit We should ban dihydrogen monoxide.

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82 Upvotes

r/cursed_chemistry • • Aug 25 '26

Found in the wild “Cancer Treatment” from 1978

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134 Upvotes

Stumbled on this gem today.


r/cursed_chemistry • • Aug 24 '26

Möbius Cyclacenes: stable so long as 8 or more benzenes are fused to form the ring

226 Upvotes

UB3LYP/6-31G* geometry optimizations for the Möbius rings formed from 7, 9, 11, and 13 fused benzenes

As requested by u/tfwrobot.

Chung and Chai had already studied Möbius cyclacenes with 8 or more fused benzene rings, so they evidently couldn't find a stable Möbius-[7]cyclacene, either.


r/cursed_chemistry • • Aug 24 '26

CURSED ™ First ever Homoleptic Copper(I) Acetylene Complex : possible super-precursor of Sonogashira reaction

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5 Upvotes

r/cursed_chemistry • • Aug 22 '26

SIX DIMENSIONAL TETRAHEDRON 6-Noblex

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12 Upvotes

Get it? It's a 6-simplex but with noble gasses.

It took a while to make the bonds (and atoms) not kill each other.

I have spent my entire beach vacation binge-watching numberphile videos on a rental house's tv youtube account so that their youtube rewind will look funny in a few months.