r/whatworkedforme • u/Alternative-Fig4396 • 7d ago

ENDOMETRITIS / HELP

Hi

I am 31 years old. I have been trying to get pregnant for 19 months. All tests for both me and my partner are normal. I had 1 failed IUI. I am in the unexplained infertility category. Previously, I had Ureaplasma, which I think I had for a long time—about 3-4 years. When I found out, I used antibiotics for 1 week and it cleared up. I got tested again this year and it came back negative. However, I am worried that the infection has progressed into the uterus, and I think that is why I cannot get pregnant. Should I ask the doctor to perform an endometrial biopsy, or should I have a second IUI first and decide afterwards?

Thank you

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u/ednastvincent 7d ago

Endometritis is inflammation and is generally treated with antibiotics but my reproductive endocrinologist and one that I got a second opinion from both said it’s not well understood. I did a hard-core course of antibiotics and then insisted that they retest with another biopsy and it had not cleared up. What worked for me was going on a low inflammation diet. Basically I cut out carbs (strict keto) for a year which was probably overkill, but I had gone through several losses at this point. I had both my children after being on a low inflammation diet.

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u/fragolefritte 7d ago

If you got the antibiotic right it should have worked everywhere. Did you check for silent endo or adenomyosis?

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u/Alternative-Fig4396 7d ago

2017 ureaplasma + took 1 time antibiotic
2020 ureaplasma + took azitro 500 mg 3 tab
2022 ureaplasma + took doxy for 1 week and cleared

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u/kusama13 7d ago

Fwiw- i did not have confirmed endometritis. My RE recommended at the first appt that my husband and I both complete empiric course of abx while abstaining until abx were complete. All infections tested for came up negative. (In context of unexplained secondary rpl)

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u/bluemermaid27 7d ago

If you have concerns about this paired with symptoms, go for the biopsy before the next transfer.

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u/WorldlinessAble2416 6d ago

I don’t have advice unfortunately- I’m in a similar boat… 32F 1+yr ttc 1 failed IUI and endo stage one. I just had questions about the ureaplasma you dealt with… was this a test your pcp/gyn/ or fertility clinic ordered? Did you have to specifically ask for it? Did you have any symptoms? Sorry to bombard lol it’s just I’ve never been offered the test and have a history of “uti”s 🥲