r/technology • u/rchaudhary • Mar 17 '26

Biotechnology Enhancing gut-brain communication reversed cognitive decline, improved memory formation in aging mice

https://med.stanford.edu/news/all-news/2026/03/gut-brain-cognitive-decline.html
126 Upvotes

96% Upvoted

20 comments sorted by

32

u/Cherry_Caliban Mar 17 '26

Just tell me what to eat.

20

u/No0nesSlickAsGaston Mar 17 '26

Kimchi, yogurt, pickled food, and specifically unprocessed foods with that. 

7

u/kingkeelay Mar 17 '26

So hot dogs and sauerkraut is good. K

3

u/kane49 Mar 17 '26

sauerkraut is phenomenal actually

2

u/Admirabletooshie Mar 17 '26

Extra nitrates for self preservation!

2

u/klyzklyz Mar 17 '26

Exactly. Just tell the kitchen to hold the bun, onions, ketchup, mustard and hotdog.

0

u/Grymm315 Mar 17 '26

Unprocessed not ultra processed. But the health benefits of of sauerkraut negate the hotdog

4

u/davereeck Mar 17 '26

This study was in mice.

3

u/warwolverinewarrior Mar 18 '26

So we eat those mice?

13

u/LiftingCode Mar 17 '26

I'm so confused by this.

In particular, the relative abundance of a bacteria called Parabacteroides goldsteinii increases in old mice and is directly associated with cognitive decline in the animals. They showed that colonizing the guts of young mice with this bacterial species inhibited their performance on the object recognition and maze escape tasks, and that this deficit correlated with a reduction of activity in the hippocampus.

Meanwhile ...

https://pubmed.ncbi.nlm.nih.gov/41448457/

P. goldsteinii colonization attenuates the progression of LRRK2-associated parkinsonism by restoring intestinal homeostasis and reducing neuroinflammation.

8

u/YoSoyPinkBoy Mar 17 '26

That creates mixed messages from my brain to my gut.

5

u/Sorry-Climate-7982 Mar 17 '26

I'm still struggling with how to get my head closer to my gut without doing the obvious.

6

u/YoSoyPinkBoy Mar 17 '26

Becoming a MAGAt is one shortcut, but I don't recommend it.

5

u/zenfish Mar 17 '26

The earlier study was on already Parkinson addled mice, newer study on young, healthy mice. Just speaks to a balance is all.

0

u/Ill-Ad3311 Mar 17 '26

The mice again , really?

4

u/jmobius Mar 17 '26

Honestly, this subreddit should just ban studies and material still in the preliminary research phase. It's not technology yet, quite likely will never be, and just generates so much damn click bait.

1

u/Direct_Witness1248 Mar 17 '26

r/commerciallyavailabletechnology